CBG Isolate is made by completely isolating the cannabidiol from all the other plant matter and compounds. It’s an extremely potent and useful ingredient that can be used to manufacture numerous products, and we have a wholesale CBG isolate deal for you!
That means all other cannabinoids, terpenes, flavonoids, and inactive compounds like plant waxes are stripped from the extract, leaving only CBG, or cannabigerol. The final product is a fine white powder that is nearly 100%, pure CBG.
If you’re trying to manufacture a product with a very specific amount of any cannabinoid in it – medication for example that would require accuracy down to the milligram, this is where you would need CBG Isolate.
CBG is quite possibly the most important cannabinoid that exists. It is a direct line to three main cannabinoids: tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), and cannabichromenic acid (CBCA).
Once exposed to heat or light in process known as decarboxylation, THCA, CBDA, and CBCA will shed their carboxyl acid group and become THC, CBD, and CBC, respectively. When it comes to CBGA though, certain enzymes break it down and it is immediately converted to THCA, CBDA, or CBCA.
This product is FDA-GMP equivalent, and it’s 99.8% pure!
This CBG Isolate comes from the West Coast, USA, and is great for use in a variety of manufactured products including supplements, vape liquids, cosmetics, and much more. Priced to sell in bulk – the more you buy, the cheaper it is per unit price.
CBG ISOLATE DEAL
We haveCBG Isolate Starting at $3,750/kilo, contact us at firstname.lastname@example.org for more information and make sure to subscribe to the CBD Flowers Business Weekly for more deals!
Cannabics Pharmeceuticals (OTCQB: CNBX) has conducted research focusing on the effect of certain cannabinoids fighting against cancer. The company, which pursues personalized cannabis-based medicines, found promising effects with two cannabinoids, CBC (Cannabichromene) and CBG (Cannabigerol.) When testing these cannabis compounds at their High Throughput Screening (HTS) facility in Israel, they found them to display anti-tumor […]
Editor’s Note: With the understanding that the current Wuhan coronavirus outbreak is related to a virus, and is therefore not treatable with antibiotics or anti-bacterials. The increase in superbug and life-threatening virus outbreaks over the last couple of decades do raise a good question towards the progression of our treatment options, and preventative measures – […]
Preliminary research suggests that cannabigerol (CBG) may be the best cannabinoid to utilize in the fight against antibiotic-resistant superbugs like MRSA.
Microbiologists from Hamilton, Ontario’s McMaster University compared CBG against THC (tetrahydrocannabinol) and CBD (cannabidiol) to see which compound was most capable of killing bacteria such as MRSA (methicillin-resistant Staphylococcus aureus). As it turns out, CBG won by a landslide.
Not only did CBG kill the MRSA microbes, but also the remaining “biofilm” that often form on patients’ skin and medical implants. The scientists in this study even went so far as to say CBG was on par with vancomycin, an antiobiotic that so far has the best results in treating drug-resistant bacteria. The study is currently under peer review by the ACS Infectious Diseases journal, but has yet to be certified or published.
Mark Blaskovich, who studies antibiotic
cannabis compounds at the University of Queensland and is reviewing the study, is
optimistic about this new discovery. He noted that cannabis plants are
particularly rich in antimicrobial compounds when compared to other botanicals
such as tea tree, garlic, and turmeric.
“These are likely made as a defense mechanism to protect the plant from bacterial and fungal infections, but to date have not been very useful for human infections as they really only work outside the body,” he said. “That’s what makes this new report potentially exciting – evidence that cannabigerol is able to treat a systemic infection in mice.”
However promising the results are though, it’s
important to remember that we’re only the beginning stages of research. Lead study author Eric Brown
noted that while cannabinoids are “clearly great drug-like compounds, far more
research is necessary before the results can be tested on human patients or
applied in medical settings.”
Start off on the right foot this harvest season by using high quality CBG seeds for your crops – potent, popular, and always legally compliant.
We currently have an amazing deal on premium, high-CBG hemp flower seeds that are testing at 18% to 21% CBGa content when grown indoors. This strain is a phenotype of a 5-year genetics, 9 iteration of CBG flowers, coming from the midwestern state of Indiana.
Genetics can be tailored to the customers specific climate, as these current ones do best in semi-arid locales. This breeder also supplements their pollen bank with 7 generation genetics, and they have the ability to stress the genetics in a controlled setting and produce specific phenotypes.
If you’re curious what the final product from these CBG seeds is expected to look like, check out the image below.
Now let’s talk numbers. Normally, these seeds sell for around $2.50 a piece but they are currently available for less than $2 each. This is an excellent investment as pounds of trimmed CBG flower are currently selling for $600-700 per pound. Compare this to only $140-170 per pound of trimmed CBD flowers. The price of CBG flower may drop a bit in the coming months, but nowhere near as much as CBD flowers did. For CBG flower, a type that is regularly compliant and sells fast, the price will remain relatively high.
We have a minimum order quantity of 25,000 seeds which will cover 10 acres at 2500-2800 seeds/acre. Anything less than this would hardly be worth the time, effort, and investment to cultivate it.
If you’re going through all the work of growing flower, you don’t want your crop to be ruined by subpar or uncompliant seeds. Get it right from the beginning.
As CBG is synthesized into other cannabinoids including THC, strains high in CBG are generally very low in other cannabinoids. That means high-CBG strains are consistent in producing less than 0.3% total THC, which is now the limit under the recently-released USDA rules for growing hemp.
Many CBD-rich varieties of hemp – especially ones with over 10-15% CBD – produce well over 0.3% THC. While this has been loosely regulated up until now, starting next year, all hemp plants must test below the reinforced limit of 0.3% total THC. This will mean many of the genetics currently used are no longer compliant with law.
As a matter of fact, most of the CBD strains on the market today are not compliant based on these standards and some farmers are dealing with having to let law enforcement destroy their crops.
Make sure this doesn’t happen to you buy getting legal flowers from the beginning.
Interested in this offer? Subscribe to the CBD Flowers Business newsletter or contact us directly at email@example.com to claim this one-of-a-kind deal.
Thanks to the 2018 farm bill and
increased awareness of the benefits of using cannabis and hemp, this plant is
once again being grown on a national scale. One of the most important aspects
of this is of course, the rapid rise of public interest in various cannabinoids.
Although CBD and THC lead the way when it comes to cannabis research, another compound is slowly making its way into the spotlight: CBG, or cannabigerol. Although studies on this cannabinoid are limited for the time being, it has enormous therapeutic potential. One of the most recent discoveries slates CBG as a powerful remedy for diminishing certain tumors.
CBGA was discovered in the 1960s by Israeli Professor, AKA the Father of
Cannabis Research, Raphael Mechoulam and one of his partners, Yehiel Gaoni. As
it turned out, CBGA, the version of CBG that still has its carboxyl acidy group
and can be found in completely raw cannabis plants, is one of the most important
cannabinoids in existence – it’s a precursor to all other cannabinoids. It has
since been rightfully dubbed, the Mother of All Cannabinoids.
Specifically, CBGA (cannabigerolic
acid) is a direct line to three main cannabinoids: tetrahydrocannabinolic acid
(THCA), cannabidiolic acid (CBDA), and cannabichromenic acid (CBCA). Once
exposed to heat or light in process known as decarboxylation, THCA, CBDA, and
CBCA will shed their carboxyl acid group and become THC, CBD, and CBC,
respectively. When it comes to CBGA though, certain enzymes break it down and
it is immediately converted to THCA, CBDA, or CBCA. This is why more THC means
less CBG, because of the unique way these compounds interact and are
Because of this, plants that do covert
to CBG will have their highest cannabigerol content early in the flowering
stage. In most cultivars, if left to fully mature, almost all CBG will be
converted into other cannabinoids. However, as mentioned above, some hemp
strains naturally produce high amounts of CBG rather than CBD or THC.
Anti-Tumor Properties of CBG
A recent press release from Cannabics Pharmaceuticals Inc. announced last week that preliminary findings from their pre-clinical trials conducted in Israel show that CBG has greater anti-tumor effects than CBGA, the acidic from of cannabigerol. Specifically, CBG was found to have an impact on human stomach and bone cancer cell lines.
According to the study, “the
HTS platform was utilized to screen the necrotic effects of
both CBG & CBGA on various types of cancer cell lines.
Interestingly, CBG was found to induce necrotic effects while
CBGA had no such effect. These findings further support previous research
performed by the company, which has consistently shown differential anti-tumor
effects when using a variety of cannabinoids on human cancer cells, derived
from both fresh biopsies and cell lines.”
This discovery could
open the door for Cannabics Pharmaceuticals to organize additional research
efforts, as well as eventually offer personalized cannabinoid therapy for patients
in the future.
Dr. Yaakov Waksman, the company’s Head of Cannabidiol
Research, had this to say on the subject: “CBG is gaining a lot of
interest as of late by the scientific community due to its potential
therapeutic properties. The recent preliminary findings from our research team
illustrate how purified cannabinoids can potentially yield anti-tumor activity
and enable us to examine the entourage effect of botanical extracts versus the
purified compounds. We are excited by these preliminary findings and plan to
perform additional experiments in the near future to further support
CBG’s Other Benefits
In addition to its anti-tumor
properties, CBG has many other potential medical benefits. Various studies on
this cannabinoid have uncovered its ability to be used as a neuroprotectant, antioxidant, and anti-inflammatory
compound. Limited research also suggests that it can effectively treat
gastrointestinal disorders and glaucoma.
study found CBG to be beneficial in
the treatment of MRSA due to its antibacterial and antifungal properties. Its
neuroprotective properties, mentioned above, may help people with Huntington’s
disease, while further research has looked into its potential to treat bladder
CBG is also being used as a safe and effective
antidepressant and its effects mimic those of SSRI medications. It’s also
believed that CBG can boost production of the endocannabinoid Anandamide, which naturally
increases dopamine levels as well as regulates various functions such as sleep,
mood, and appetite.
How To Find CBG
Although some companies
are already advertising CBG oil for sale, the effectiveness (and safety) of these
products remains to be known. As of now, the most popular way to get your dose
of CBG is through good ole’ fashioned flowers. Although CBG-dominant flowers
are anything but old fashioned, the act of smoking of vaporizing natural
cannabis or hemp buds still remains to go-to method for most consumers.
Because this is a
relatively new trend, knowing where to find these flowers can be a challenge.
Of course, you want to find a company that has good quality buds for a
reasonable price. You also want them to be reliable and have good customer
service should an issue arise. Multiple hemp flower retailers are selling
different CBG strains on their websites, many of which have great reviews, but
it can still be difficult to know what is legit and what isn’t in today’s
This is why we’ve put together a couple of newsletters to help you find exactly what you’re looking for. If you’re a consumer, we have the CBD Flowers Weekly to bring you deals on all the best hemp flowers. If you’re buying flowers for resale, we’ve created the CBD Flowers Business Newsletter – a weekly subscription that has various pound and wholesale deals.
Subscribe to the newsletter of your choosing and check your email every Thursday morning to learn more about hemp flowers!
It is the middle of September and the heat is intense, sweat is dripping down my forehead as I walk down rows of plants that seem to never end. Myself and my crew, which includes my bandmate Bleezy from our rap group Mendo Dope and our business partner Mark Greyshock of Greenshock Farms, are just finishing up the biggest pheno hunt that any of us have ever done. Our noses are covered in resin after closely examining about 800 plants, searching for the next top strain among the phenos. We literally cannot smell anymore, our nostril hairs are sticky and the tips of our noses are raw.
As the sun sets, the colors in the sky are unreal, almost as if the clouds themselves were on fire glowing in a bright orange. We roll up a Backwood of Sour Apple bud, pack our gear and get ready to head out, reeking of fresh ganja. The road is winding, swerving through the rolling hills with such sharpness that it almost feels like we are on mushrooms as we drive into the night sky.
“We found some winners today,” Bleezy says, still smelling the tips of his fingers that are completely covered in resin.
The Road Before Us
Pheno hunting and creating new strains is a lengthy process. Greyshock explains that creating the award-winning Tropical Sleigh Ride strain came after many years of hard work.
“It all started with the Purple Candy Cane, which has placed in the top three at the Emerald Cup two years in a row,” he says of the strain’s lineage. “We got a hold of a Pineapple plant from [noted California cannabis breeder] Mean Gene and just out of intuition, I knew that there was going to be a winner by crossing these two plants.”
The strain was created in 2016 and grown for the first time during the 2017 harvest. Greyshock says he had more confidence in this particular breeding project than others he has worked on in the past. This confidence was due, in part, to the strain’s unique terpene profile. In fact, in 2017, Greenshock’s Tropical Sleigh Ride won the highest total terpene content award at the prestigious Emerald Cup, with 4.8% terpenes.
The fruit-forward Tropical Sleigh Ride has an ocimene-dominant terpene profile, something that is also found in other plants such as basil, bergamot and lavender. In addition, it has a high level of CBG (a cannabinoid that is a precursor to both THC and CBD), generally 2 to 2.5 %.
“It has an overall very high cannabinoid ratio with the THC itself in the neighborhood of 17% at its lowest and all the way up to 27-28%,” Greyshock says. “With high levels of both terpenes and cannabinoids in one plant, it makes this strain a very dynamic combination. The smell and flavor of this flower is unlike any other.”
It’s an uplifting strain with a woodsy, floral and tropical smell (think oranges, mangos, guava, pineapple, papaya, lemons and hints of pine) that could be applicable to lift a depressive fog, he says.
“Tropical Sleigh Ride makes you feel happy to be alive. It crushes negativity and brings out positivity. I would say its best medical trait would be treating depression,” Greyshock says. “The flavor is truly delicious and just smelling it will make you feel good. Smoking the Tropical Sleigh Ride is like snowboarding down a mountain of fruit, carving through oranges and mangos jumping over pine trees.”
And, in terms of its growth, Greyshock says the vigorous fast-growing Tropical Sleigh Ride is extremely adaptable.
“It handles a variety of conditions very well, performing great in all environments,” he says. “Here in California, we have grown it in the Sierras at 4,200 feet [elevation] and it grew very nicely. This year, we are growing it in San Luis Obispo County in a very hot and dry climate that reaches temperatures of 110 degrees regularly and it is performing great.”
Greyshock says the strain also possess a strong resistance to both bugs and mold, something that becomes very important when picking the winners from a new batch of plants. The buds themselves are generally very solid and chunky.
“Even with the sativa influence, these buds are not loose at all — they are very tight sativa buds,” Greyshock says. “We have had plants started from seed that have grown over 12 feet tall and 10 feet wide, towering over our heads, so she can definitely grow big. One of this strain’s best traits is its ability to fight off mold.”
Two Birds of a Feather
When it comes to the variations in phenotypes on this strain, Greyshock explains there are two basic types: the green pheno and the purple pheno.
“The purple pheno shows a lot of color on the leaves and stalk and a decent amount on the bud,” he says. “About 40% of the phenos exhibit the green version of this strain. One pheno that we love is the Passion Orange Guava (POG) and that is an example of a green variation. Another pheno we have took sixth place [in the sungrown category] at the 2018 Emerald Cup and this one has more of a purple influence that we call the Hawaiian Punch pheno.”
And when it comes to picking which pheno is best, you might as well ask a mother which daughter she favors more.
“It is hard to say which variation is better, both purple and green phenos are phenomenal,” Greyshock says. “In terms of the overall size of the buds, I’d say about 10% of the phenos have large big buds and those aren’t generally the ones we keep. It seems to be the tighter, medium, chunky phenos that we are after a lot, which fortunately the majority come out to be.”
Even though the Tropical Sleigh Ride is a fabulous smoke, cannabis breeders are almost always interested in taking their strain further.
“Once you have these type of plants in your collection, it is always about trying to make new and better things if you can,” Greyshock says. “Right now, we are playing around with the Tropical Sleigh Ride. This last year, we crossed it with another phenomenal California plant that was bred right here in Mendocino County called the Long Valley Royal Kush. Both of these plants have won awards at the Emerald Cup, so the combination of these two plants is making for some really exciting stuff this year.”
Breeder: Greenshock Farms
Genetics: Purple Candy Cane x Pineapple
Yield: Medium to Heavy
Height: Medium to Tall
Harvest Time: 56 to 60 Days
Profile: Sativa 70%/Indica 30%
TELL US, would you be interested in trying a strain bursting with tropical terps?
Originally published in Issue 40 of Cannabis Now. LEARN MORE
Last week, researchers from the University of Salento in Italy discovered two new cannabinoids. The compounds have been deemed tetrahydrocannabiphorol (THCP) and cannabidiphorol (CBDP). What’s interesting about THCP is that it is apparently 30 times stronger than THC. However, nobody is yet to understand what this really means in the grand scheme of cannabis science. The only thing the ganja geeks can say for sure is that this new compound appears to be more prevalent than THC when given to mice. They also believe the presence of THCP could be what provides cannabis strains with varying effects. In other words, we have two new cannabinoids — one that may even be the real rockstar — and we still know very little about their roles or what they are capable of.
Until now, all the scientific sector has really known is that there are hundreds of cannabinoids getting down to business in the cannabis plant. It just so happens, though, that when it comes to how this plant works when providing a buzz, healing, curing or whatever it is a person needs it to do, THC and CBD have been given all the credit. Still, we have known for a long time that the presence of unsung cannabinoids, like cannabinol (CBN) and cannabigerol (CBG), are responsible for helping to produce unique effects. There is also a little something called the entourage effect, whereby all of these compounds work together in harmony to create a certain kind of magic. Yet, we have continued the course in making THC and CBD the focal point of the spiel. Scientists now believe that at least one of the new cannabinoids, THCP, could also prove to have substantial benefits.
“A number of clinical trials and a growing body of literature provide real evidence of the pharmacological potential of cannabis and cannabinoids on a wide range of disorders from sleep to anxiety, multiple sclerosis, autism and neuropathic pain,” researchers said. “In particular, being the most potent psychotropic cannabinoid, THC is the main focus of such studies.”
“THCP is endowed of an even higher binding affinity for CB1 receptor and a greater cannabimimetic activity than THC itself.”
Although the wheels might be turning in the brains of cannabis industry executives curious about whether the discovery of CBDP might provide them with a new revenue stream, scientists argue that it might not be worth it. At least not yet. It seems the compound is wonky (it doesn’t bind well to CB1 or CB2 receptors). Therefore it is not something they are interested in learning more about right away. “In our opinion, this compound should be included in the list of the main phytocannabinoids to be determined for a correct evaluation of the pharmacological effect of the cannabis extracts administered to patients,” researchers explained.
In the end, the discovery of two new cannabinoids means there is still a wealth of opportunity to learn about what makes cannabis tick. But the longer the federal government keeps trying to separate these compounds into good and bad — CBD is medicine, THC is the devil — the longer it’s going to be before anyone of us has a real understanding about what happens when we consume this plant.
TELL US, do you think you could handle a cannabinoid with 30 times of the potency of THC?
Glaucoma was one of the very first
conditions to be treated with medical cannabis, but over time it’s been
determined that certain cannabinoids can make the condition worse.
Back in 1971, Hepler and Frank reported a 25–30% drop in intraocular eye pressure in a small number of subjects who had recently smoke cannabis. To this day, glaucoma is still a commonly cited reason for prescribing medical cannabis.
When it comes to glaucoma, the cannabinoid most commonly associated with healthcare – CBD – is actually detrimental to this condition. Historically, THC has been successful treatment option, but new studies indicate that another cannabinoid might be even more effective – CBG or cannabigerol.
Glaucoma is a condition categorized by
increased pressure in the eye, called intraocular eye pressure, caused by fluid
buildup in the front part of the eye. Over time, the pressure builds up and
damages the optic nerve, which is what sends images from your eyes to your
brain. This can eventually lead to blindness.
Glaucoma is the second-leading cause
of blindness in the United States. There are certain criteria that make certain
people predisposed to glaucoma. It’s more likely to effect African Americans
and Hispanics, and it’s there is an elevated risk for people who have a family
history of this condition. Other risk factors include: thinner corneas, chronic
eye inflammation and certain medications.
Glaucoma effects more than 3 million
Americans, 2.7 million of whom are over the age of 40. Although it primarily effects
adults, there is an infant (congenital) form that exists. There are two main
types of glaucoma: Primary open-angle glaucoma, which happens gradually over a
long period of time; and Angle-closure glaucoma, which is acute onset and
considered a true ocular emergency.
What is CBG?
Since cannabigerol is usually only
present in cannabis in very small amounts – normally less than 1 percent – it’s
considered a minor cannabinoid. CBG is important for another reason though, and
that is its ability to synthesize other major cannabinoids. Because of this, CBGA
(cannabigerolic acid) has been appropriately nicknamed “The Mother of
CBGA is a direct line to three main cannabinoids:
tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), and
cannabichromenic acid (CBCA). Once exposed to heat or light during a process referred
to as decarboxylation, THCA, CBDA, and CBCA will shed their carboxyl acid group
and become THC, CBD, and CBC, respectively
If we’re following the pattern above, CBGA should break down to CBG, but this doesn’t happen very often. Usually, certain enzymes break down CBGA and it is immediately converted to THCA, CBDA, or CBCA. This is why more THC means less CBG, because of the unique way these compounds interact and are synthesized.
However, in certain strains, CBGA naturally converts to CBG. These strains are low in THC and easily able to pass compliance standards. To get more flowers with these high levels of CBG, breeders are practicing plant cross-breeding and other forms of genetic manipulation.
The Research: CBG for Glaucoma
CBG may also help with treating
glaucoma, because of the way it reduces intraocular pressure. Our eyes contain
many endocannabinoid receptors which can be activated by cannabinoids like CBG.
When activated, the result can be a shift in intraocular pressure. While cannabinoids
in general have been suggested as helpful for this, some studies show that CBG
may be particularly helpful with decreasing pressure and expediting the
draining of fluids.
A study https://www.ncbi.nlm.nih.gov/pubmed/1965836 conducted by the Department of Ophthalmology at
West Virginia University Health Sciences Center North in Morgantown, determined
that “After chronic administration of CBG unilaterally to the cornea via Alzet
osmotic minipumps and connecting extraocular cannulas, a considerable fall in
ocular tension amounting to 4 to 7 mm Hg occurred. Both CBG and THC produced a
two-to three-fold increase in aqueous outflow facility. These results suggest
that cannabigerol and related cannabinoids may have therapeutic potential for
the treatment of glaucoma.”
CBG is cannabinoid that hasn’t gotten much attention but seems to have very much therapeutic value, and this is especially true when it comes to treating glaucoma, which can be a completely debilitating condition. Endocannabinoid receptors are prevalent in eye structures, and interestingly, CBG is thought to be particularly effective in treating glaucoma because it reduces intraocular pressure. It is a powerful vasodilator and has neuroprotective effects to boot.
The age-old excuse, “it’s for my glaucoma.” Back when cannabis was stigmatized, CBD was not as well known and people relied on THC strains for everything. In the full and broad spectrum world of cannabis, there are only so many reasons for intoxication left. Remedies for deliberating conditions like Glaucoma and even acne may not […]