Study: Self-Made Human Cannabinoids May Be Key To Treating Stress-Related Disorders

We already know that humans have our own endocannabinoid systems, made to regulate a number of bodily functions with a number of cannabinoid receptors that interact with compounds like THC and CBD in cannabis. 

Brain activity patterns and neural circuits regulated by these cannabinoids derived in the brain were not well known, but new research has revealed our bodies may actually release their own cannabinoid molecules in specific circumstances, independent of external cannabinoid use.

According to a new mice study from Northwestern Medicine published in the journal Cell Reports, the brain’s key emotional center, the amygdala, releases its own cannabinoid molecules under stress. When released, these molecules work to decrease incoming stress alarms from the hippocampus, which controls memory and emotions in the brain.

The study results add further evidence to the assertion that the brain contains innate cannabinoid molecules, key to our body’s natural coping response to stress. Further, the study may indicate that impairments to this endogenous (the body’s own) cannabinoid signaling system in the brain could result in higher susceptibility to developing psychiatric disorders related to stress, like depression and post-traumatic stress disorder (PTSD).

Still, further research is needed to determine exactly how these mechanisms work in the human brain, said corresponding study author Dr. Sachin Patel.

The Human Body’s Self-Made Cannabinoids and Understanding Stress

“Stress exposure confers risk for the development or exacerbation of psychiatric disorders: from generalized anxiety and major depression to post-traumatic stress disorder,” authors state in the introduction. “Understanding stress-induced molecular-, cellular-, and circuit-level adaptations could provide critical insight into how stress is translated into affective pathology and may reveal novel therapeutic targets for the treatment of stress-related disorders.”

Scientists at Northwestern Medicine used a new protein sensor that can detect the presence of these cannabinoid molecules in real time at specific brain synapses, which show that specific high-frequency patterns of amygdala activity can generate the molecules. Additionally, the sensor showed that mice brains released these molecules in response to several different types of stress.

Scientists also removed the target of these cannabinoids, the cannabinoid receptor type 1, which resulted in a worsened ability to cope with stress and motivational deficits in mice. After scientists removed the receptor target of the endogenous cannabinoids at hippocampal-amygdala synapses, mice adopted more passive and immobile responses to stress. They also had a lower preference to drink sweetened sucrose water after stress exposure.

“Understanding how the brain adapts to stress at the molecular, cellular and circuit level could provide critical insight into how stress is translated into mood disorders and may reveal novel therapeutic targets for the treatment of stress-related disorders,” according to Patel and Lizzie Gilman, Professor of Psychiatry and Behavioral Sciences and a Northwestern Medicine psychiatrist. 

The endocannabinoid system is one of the leading signaling systems identified as a prominent drug-development candidate for stress-related psychiatric disorders, Patel said. This system is an active, complex cell signaling network, involving a combination of endocannabinoids, enzymes and cannabinoid receptors helping to regulate a number of biological functions — like eating, anxiety, learning, memory, reproduction, metabolism, growth and development — through an array of actions across the nervous system.

This hypothesis is crucial in determining where future research guides this continued conversation, Patel said.

“Determining whether increasing levels of endogenous cannabinoids can be used as potential therapeutics for stress-related disorders is a next logical step from this study and our previous work,” Patel said. “There are ongoing clinical trials in this area that may be able to answer this question in the near future.”

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Federal Judge in Arkansas Blocks Hemp Cannabinoids Ban in Pivotal Ruling

The implications of a recent federal judge ruling have people in the industry asking: Did a federal judge just legalize help-derived cannabinoids like delta-8 THC, HHC, THCP, and THCa flower? In a nutshell, a judge in Arkansas ruled that the 2018 Farm Bill takes legal precedence over an Arkansas state ban on hemp-derived cannabinoids, which could lay out a blueprint for future legal actions in other states.

On Thursday, U.S. District Judge Billy Roy Wilson ruled to block the enforcement of Act 629 of 2023, which was passed in Arkansas in the 2023 legislative session and banned sales and production of items containing delta-8, delta-9, and delta-10 THC in the state. The judge found the hemp product ban to be conflicting and arbitrary. 

Act 629 was approved in the 2023 regular session of the state’s General Assembly, and it seeks to ban the production and sale of products containing delta-8, delta-9 and delta-10 as well as other THC isomers derived from hemp. Arkansas Gov. Sarah Huckabee Sanders signed Act 629 earlier this year, which bans “poorly regulated products” derived from hemp.

For the time being, hemp sellers in the state are celebrating it as a win. Award-winning attorney Rod Knight believes it could have significant implications for hemp laws in every state, not just Arkansas.

Four Plaintiffs in Arkansas Sue

Four businesses—Bio Gen LLC, Drippers Vape Shop LLC, The Cigarette Store LLC, and Sky Marketing Corp—filed a lawsuit  earlier this month. The companies spoke from several points of the hemp industry chain: a manufacturer, wholesaler, distributor, and retailer. 

Gov. Huckabee Sanders, Attorney General Tim Griffin, Dept. of Finance and Administration, Tobacco Control Board, Dept. Agriculture, State Plant Board, as well as the prosecuting attorneys of the state’s 28 judicial circuits, are all named as defendants in the lawsuit.

Lawyers representing those businesses argued that the law was unconstitutionally vague and that it was preempted by the 2018 Farm Bill. It appears that their argument holds up.

“Plaintiffs have been, and will be, harmed by Act 629,” the complaint reads, according to a report from the Northwest Arkansas Democrat-Gazette, “as they are unable to transport in and through Arkansas hemp-derived cannabinoid products that have been declared legal under federal law.”

Senate Bill 358 was approved and enacted on April 11 as Act 629, and it criminalized all hemp-derived products “produced as a result of a synthetic chemical process” and “[a]ny other psychoactive substance derived therein.” 

But the plaintiffs argue that the Act is superseded by the 2018 Farm Bill and also that its provisions are unconstitutionally vague and therefore void. The Court agreed and entered an injunction that blocks the enforcement of the Act. 

Abtin Mehdizadegan, an attorney representing the plaintiffs, said that his clients tried to avoid legal action before the ban was signed into law.

“Our suit asks the federal court in the Eastern District of Arkansas to enjoin the entirety of Act 629 because it unconstitutionally narrowed the definition of hemp-derived products in violation of the 2018 Farm Bill and impermissibly restricted the transportation and shipment of these products,” Mehdizadegan wrote. “Before the bill was signed into law, we had lengthy dialogues with the defendants during the 2023 legislative session as the bill was making its way through the legislative process.” 

Preempted by 2018 Farm Bill

In its ruling, the Court made three specific conclusions: that the Act is preempted by federal law under the principle of “conflict preemption”, that the Act is preempted by federal law under the principle of “express preemption”, and third, that the Act is unconstitutionally vague and thus void. 

Attorney Rod Knight explained that the Court’s first two findings are based on the legal doctrine of preemption. As the court states, “the federal preemption doctrine stems from the Constitution’s Supremacy Clause, which states that laws of the United States made under the Constitution are the supreme law of the land. State laws that interfere with, or are contrary to the laws of congress, made in pursuance of the constitution are invalid or preempted.” 

There are several types of preemption, and regarding this case, the Court found that two are applicable: “conflict preemption” and “express preemption”. Although similar in their effect, they are based on different premises. The court’s third finding is based on a separate legal doctrine referred to as “void for vagueness” under the due process clause of the Constitution.

Last May, Arkansas became the latest state with a legal cannabis industry to regulate or ban intoxicating hemp-derived products, and they’ve been on shelves since the 2018 Farm Bill legalized hemp production nationwide. Arkansas adopted the 2018 Farm Bill locally through the Industrial Hemp Act 565.

Local news agency KTHV reports that the case is set to go to trial on Aug. 27, 2024.

Congress is set to review the Farm Bill again this year, and there’s a possibility that federal lawmakers could address the unintended rise of hemp-derived cannabinoids, particularly intoxicating ones.

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Researchers Address Benefits of Cannabinoid Properties for Various Skin Conditions

A study published in the journal Molecules on Aug. 20, entitled “Therapeutic Potential of Minor Cannabinoids in Dermatological Diseases—A Synthetic Review,” put the spotlight on various cannabinoids as a method to help treat specific dermatological diseases.

Polish researchers Emilia Kwiecień and Dorota Kowalczuk from the Medical University of Lublin and chemistry lab, A-Sense, analyzed medical studies published in other scientific journals and found that cannabinoids “exhibit diverse pharmacological activities, including anti-inflammatory, analgesic, antimicrobial, and anti-itch properties.”

They researched the effects of CBDV, CBDP, CBC, THCV, CBGA, CBG, and CBN, as well as CBM (cannabimovone) and CBE (cannabielsoin). “Several studies have reported their efficacy in mitigating symptoms associated with dermatological diseases such as psoriasis, eczema, acne, and pruritus,” the researchers wrote. “Furthermore, minor cannabinoids have shown potential in regulating sebum production, a crucial factor in acne pathogenesis.”

“The findings of this review suggest that minor cannabinoids hold therapeutic promise in the management of dermatological diseases,” researchers wrote. “Incorporating minor cannabinoids into dermatological therapies could potentially offer novel treatment options of patients and improve their overall well-being.”

Within the analysis, researchers noted that specific cannabinoids were more effective at treating specific conditions. CBDV has significant anti-inflammatory properties, and can be useful to address skin issues such as itching or swelling in relation to atopic dermatitis (AD). The same properties are also found to be useful in treating acne lesions because of its “anti-inflammatory and antioxidant properties.”

The anti-inflammatory properties of cannabinoids like CBM and CBE are a “novel alternative” for conducting research. “Similarly, CBC, with its anti-inflammatory and antioxidant effects, may have a beneficial impact on the treatment of acne, psoriasis, and AD,” the study stated.

THCV “shows many promising properties in combatting acne” by reducing sebum, or an oily substance produced by the body to hydrate and protect skin. “Additionally, THCV exhibits anti-inflammatory and antibacterial properties that can help alleviate inflammation and combat the bacteria responsible for acne development,” the authors continued, noting that studies on mice have found THCV to treat “metabolic and neurological disorders.”

A well-balanced, regulated endocannabinoid system is important, and researchers made a connection between this and healthy skin. “Increasing evidence suggests that endocannabinoid signaling plays a crucial role in regulating biological processes in the skin,” researchers explained. “Many skin functions, such as immune response, cell proliferation, differentiation, and survival, are at least partially regulated by the endocannabinoid system, and suppressing skin inflammation is one of its strongest functions.”

Researchers even claim that topical applications of cannabinoids, similar to melatonin and secosteroids, could potentially “…mitigate skin aging effects through targeted interaction with receptors and enzymes.”

Kwiecień and Kowalczuk still note that more studies are needed in order to explore these observations in more depth. “The impact on the nervous system, issues pertaining to product quality and regulation, as well as ethical and legal aspects, including those concerning legality, require comprehensive consideration,” the researchers wrote. “Therefore, despite the promising therapeutic prospects, the utilization of cannabinoids, especially the minor cannabinoids, necessitates further research, regulations and a balanced approach to ensure benefits while minimizing potential health and societal risks.”

Other studies have analyzed how cannabinoids help treat common skin conditions. The National Psoriasis Foundation shows that more than eight million people in the U.S. suffer from psoriasis, which is caused by an overactive immune system that leaves raised, scaly patches on skin that itch, burn and sting. Another study published in Molecules earlier this year in February found “that there is a real future for the use of hemp ingredients in the treatment of skin diseases, including psoriasis.”

Another study published in 2020 in Clinical, Cosmetic, Investigational Dermatology found that some cannabinoids’ anti-inflammatory properties could treat eczema or AD. According to the National Eczema Association, one in every 10 individuals suffer from some form of eczema in their lifetime, and 16.5 million U.S. adults suffer from AD (which is a form of eczema).

In the case of acne, which affects more than 50 million Americans annually according to the American Academy of Dermatology Association, a study published in 2022 in the Journal of Inflammation Research showed that “the use of CBD for reducing inflammation in acne is supported and should be further explored.”

There has been an increase in hemp and cannabis skincare products (both for medical and non-medical use) following the passage of the 2018 Hemp Farm Bill, although many reports began covering cannabis as the newest hot skincare ingredient back in 2016 and earlier. Since then, brands such as Lord Jones, Saint Jane, and so many more have ramped up production on CBD-based products. Eventually, some of these products made their way into major retailers such as Sephora, Ulta, and Target.

In January 2022, Martha Stewart launched her own topical CBD line with Canopy Growth, called Martha Stewart CBD Wellness Topicals, with products focused on increased strength for muscle recovery, improved sleep, and stress management.

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How Many Hemp-Derived Cannabinoids Does It Take To Screw in a Lightbulb?

Things have taken a very strange turn in the saga of the cannabis plant, as if anyone needed an extra dose of weirdness added to the mix. A loophole in the Farm Bill passed in 2018 has inadvertently created a huge money grab for hemp producers: hemp-derived cannabinoids which are isolated, concentrated and put into gummies, vapes, sprays and any number of other consumables able to be sold all across America and overseas.

This fun little segment of American hemp history has turned into a smorgasbord of strange new compounds designated with odd combinations of numbers and letters which can be daunting to almost any American consumer such as Delta-8 THC, THC-O, HHC, CBGA etc. I too have found myself “sketched out” as the kids say by smoke shop remedies for a good long while. Not because they’re all bad. The kratom conversation is insufferable to say the least but it does manage to, very occasionally, help people get off opiates, so I don’t want to detract from the value of allowing products that exist because of convenient loopholes to be sold. However, I do want to use all of my powers and skills to disseminate information that may help consumers be safer when trying diet highs and wavy supplements from their local Cheaper Cigarettes store. Harm reduction is the name of the game!

I reached out to some players in the hemp-derived cannabinoid space, which for timeliness sake will henceforth be referred to as “HDC’s” because I find mundane tasks reprehensible. I spoke to two gentlemen on the record and one off, all of whom are owners and/or operators of some of the largest if not the largest companies in the HDC space, so to speak and I have been enlightened to the ways of the weird weed chemicals.

I shouldn’t even call them that. Let’s back up. To begin with, we need to understand the difference between “hemp” and “marijuana.” Scientifically, biologically and logically speaking, there is absolutely no distinction other than the legal designations they have received. They are the same plant from the same family and the only difference is hemp plants have been bred to have low THC, making them legal under the current limit of .3% THC, and commercial cannabis has been bred to have high THC. 

“It’s all cannabis, regardless of the concentration of one arbitrary chemical constituent,” said Matthew Guenther, President of the American Cannabinoid Association. “What the passing of the Farm Bill has proven is that 0.3% Delta-9 THC was always an arbitrary limit.

The ancestral lineages/locations of origin of hemp vs what people generally consider to be marijuana are probably different, sure, but everything has been so hybridized over the years that making a distinction at this stage in the game is pointless. This is why the Indica/Sativa classifications are somewhat controversial, because they are misnomers at best (WEIRDOS has covered all of this if you want to follow these nice juicy looking hyperlinks). 

As such, when the laws classifying hemp and marijuana were written they were written based on Delta-9 THC percentage, meaning anything above .3% Delta-9 THC was illegal and known as “marijuana” and anything below that threshold is considered hemp. So when the 2018 Farm Bill legalized “hemp,” it opened up the floodgates for, by one industry executive’s count, 42 newly isolated compounds from the cannabis/hemp plant.

“They all start with hemp, not all of them are necessarily extracted directly out of the hemp plant. Most minor cannabinoids such as CBN, THCv, Delta-8 THC, Hemp Derived Delta-9 THC, THCp, CBGa isolate, CBDa isolate, you have to make through an isomerization process, hydrogenation, pressure reaction, or through other semi synthetic processes.” said Bret Worley, CEO of MC Nutraceuticals. “In order to make a Delta-8 molecule, you take CBD, through a ring closure reaction you create Delta-8 THC catalyzed by acidic conditions in heptane. After the ring closure reaction you neutralize the solution, remove the solvent and distill.”

The effects of these compounds are hard to generalize as there are, at the risk of being redundant, kind of a lot of them now but from what I’ve pieced together from in person testimonies it’s almost like if a traditional cannabis experience was a big pie, each minor cannabinoid is a tiny piece of that pie. You’re not going to get the whole experience but you’ll get a piece of it. 

“I have a high tolerance so I didn’t expect much but I did feel something. I wouldn’t really call it a high though, it honestly felt more like benzos,” a friend of mine relayed to me regarding his experience with Delta-8 gummies. Another told me it felt the exact same as weed to her and that she bought it in a smoke shop semi-unknowingly.

“It’s still psychoactive, obviously, but I see it more as like a soccer mom weed,” Worley said, referring to Delta-8 THC.

Some of these compounds, like CBN, seem to be good for sleep. Some of them seem to be good for digestion, and some of them may have the potential to help fight cancer, etc. etc. The problem is we don’t really know enough yet to be able to firmly say those things or speak to their safety. That said, no one I talked to who had money on the line seemed worried about the possibility of long-term repercussions, they seemed excited to find out more.

“That’s why it’s important that federal regulations are put in place to regulate what is essentially an entire new class of consumer product,” Guenther said. “What we’re fighting for is for the federal government to get involved and actively regulate the products we know are currently safe and effective, so that people don’t start producing and keep producing unknown untested compounds.”

Guenther referenced the Spice and K2 epidemic, which for those who don’t remember had some VERY strange and unwanted effects on its users. That’s not what HDC’s are. Spice and K2 are synthetic cannabinoids, which the National Institute on Drug Abuse has the following definition of:

“Synthetic cannabinoids are human-made mind-altering chemicals that are either sprayed on dried, shredded plant material so they can be smoked or sold as liquids to be vaporized and inhaled in e-cigarettes and other devices. These products are also known as herbal or liquid incense. These chemicals are called cannabinoids because they are similar to chemicals found in the marijuana plant. Because of this similarity, synthetic cannabinoids are sometimes misleadingly called synthetic marijuana (or fake weed), and they are often marketed as safe, legal alternatives to that drug.”

These differ from HDC’s because HDC’s are ultimately derived from the cannabis/hemp plant itself whereas synthetic cannabinoids are not.

One very interesting and unexpected result of this whole confusing mad scientist clusterfuck is apparently: weed is legal?

If you’ve noticed any “THCA flower” in your local smoke shop, that’s (probably) not hemp flower sprayed with weird chemicals, it’s just weed that was processed and tested a certain way so that the “THCA” in the flower does not decarboxylate and convert to “Delta 9-THC.” In certain states, they don’t have laws about “total THC limit” they have laws about Delta 9-THC because that’s the one that has traditionally been associated with the “high.” Thus, Donald Trump sorta kinda made it legal to ship, sell, and consume weed in a lot of states that have some of the strictest “marijuana” laws. Do you see where I’m going with this? 

It doesn’t stop there. There is technically regular ol’ Delta-9 THC in “hemp” plants. Since the plant itself tested under .3% THC, any Delta-9 THC extracted from it is perfectly legal.

“They’re absolutely identical. It is the exact same chemical as Delta-9 THC. It’s just a much more effective way of getting there,” Guenther said.

Wheels are in motion on the federal level regarding HDC’s and no one is quite sure which way things are going to go. The DEA and FDA appear to be working on regulations and rules but their official commentary has been limited. The DEA considers Delta-8 to be a controlled substance and DEA Drug & Chemical Evaluation Section Chief Terrence Boos said in February that Delta-8 THCO and Delta-9 THCO are illegal because they can only be produced synthetically. The FDA is also supposed to release rules about Delta-8 and other minor cannabinoids sometime soon, not to mention the long anticipated federal movements on cannabis legalization or re/descheduling.

In other words, nobody knows what the hell is going on! We basically have two markets right now, the legal hemp market where they can kind of sell weed (to the tune of a huge profit) but consumers don’t really know what it is and then the individual state cannabis markets where operators are getting creamed, over-regulated and over-taxed but consumers know what they’re buying. Eventually those two markets have to merge, and the way that plays out depends on what the feds do. Don’t change that channel folks, the next episode of marijuana madness will begin shortly after a brief period of utter confusion.

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Cannabis Analyzer Chosen by FDA for Quick, Accurate Product Testing

The U.S. Food and Drug Administration (FDA) announced on Aug. 18 that it has chosen a very specific company’s portable cannabis analyzer to be used to test cannabis plants as well as products.

The analyzer was created by Orange Photonics, which utilizes spectroscopy and liquid chromatography in its LightLab 3 High Sensitivity (HS) Cannabis Analyzer. The FDA plans to “…to play a pivotal role in its efforts to regulate the national cannabis industry,” a press release stated.

Previously, the LightLab 3 HS Cannabis Analyzer was chosen by the U.S. Customs and Border Protection Agency (CPB) in 2022 to be its chosen field-deployable analyzer.

“Previous to this award, the U.S. Customs and Border Protection’s Laboratories and Scientific Services conducted a multi-phase assessment of LightLab 3 Cannabis Analyzer,” said Orange Photonics President Stephanie McArdle. “Unlike general purpose, laboratory-based HPLCs, LightLab is built to analyze cannabinoids which translates into a simplified workflow, affordability, and impressive analytical capabilities.

Year-to-date data as of September 2021 showed that the analyzer helped law enforcement confiscate $2 billion worth of illicit cannabis plants and products. At the time, Josephine County Sheriff Detective Kile Henrich praised the technology for quickly identifying the differences between cannabis or hemp. “Any region that has a drug enforcement operation should use the LightLab Cannabis Analyzer,” said Henrich. “LightLab saves time on having to take confiscated cannabis to a crime lab, a process which can take 30 days versus minutes for a test on-site. It saves months and prevents future lawsuits.”

According to Orange Photonics, the LightLab 3 “decreases the burden on forensic laboratories” by allowing the device to be simple to use, and test plants and products on-site where they are grown or manufactured, to provide instant results.

“The public deserves to have complete confidence in the safety, labeling, and marketing standards of products on retail shelves. State regulatory agencies have successfully relied upon the LightLab 3 Cannabis Analyzer technology for years,” said McArdle. “The FDA’s adoption of LightLab 3 Cannabis Analyzer is a positive step as it continues to prioritize public health within the current regulatory landscape.”

Orange Photonics offers three versions of the analyzer: the LightLab 3 Cannabis Analyzer, LightLab 3 High Sensitivity, and LightLab 3 Law Enforcement version, which roughly analyzes in 10.5 minutes.

All of which can quickly analyze up to 19 cannabinoids, including Delta-9 THC, THCA, CBD, CBDA, CBN, CBG, and CBGA, in addition to others included in a “minors module.”

LightLab 3 can detect cannabis up to 0.5% (or 0.05% with the hemp compliance module), High Sensitivity up to 0.00017%/1.7ppm, and Law Enforcement version up to 0.5% (or 0.05% with the hemp compliance module).

What differs between each of the analyzers is the sample type. While the basic cannabis analyzer can test finished plant/flower, young plants, concentrates, tinctures, raffinate, and hemp compliance, the High Sensitivity version can also analyze beverage enhancers, baked goods, infused candies, pet treats, nano emulsions, and more. The Law Enforcement version focuses on dried plant/flower, young/wet plants, concentrates, edibles, and hemp compliance.

Orange Photonics’ product targets the need for quick and accurate product testing in order to maintain consumer safety. It cites the fact that over the past six years, the FDA has had to issue countless letters and safety notices to companies when they do not follow FDA regulations.

Orange Photonics plans to make numerous appearances at upcoming conventions through the rest of the year, including the California Cannabis Enforcement Summit (Aug. 22-24), TeeHC Open in Massachusetts (Sept. 8), International Drug Enforcement Conference XXXVII in Jamaica (Sept. 22), MJ Unpacked in Michigan (Oct. 10-12), and 12th Annual MJBizCon in Nevada (Nov. 28-Dec. 1).

While the LightLab 3 could play an important part in how the cannabis industry tests its products in the future, it does not affect the realm of testing in relation to the human body. Countless individuals have been punished due to THC being detected in their bloodstream long after they have consumed it.

The topic of cannabis being used as a performance-enhancing drug has been frequently revisited over the years, as many athletes have either come out in support of medical cannabis to treat sports-related conditions or dedicated themselves to the cause by creating their own cannabis brand. One of the most recent examples of this is with New Zealand-based rugby athlete, Isaia Walker-Leawere who received a one-month suspension and agreed to attend a treatment program.

Positive drug tests also negatively affect non-athletes frequently as well, with studies stating that positive workplace drug tests are at the highest levels in the past 25 years. Fortunately, some states are implementing rules to protect consumers. In Michigan, a civil service commission approved a new rule stating that no longer disqualify applicants for state positions in July.

Some legislators are also taking a stance on cannabis testing, such as Rep. Matt Gaetz recently called for putting an end to cannabis testing for military members last month. One New Jersey officer who tested positive for cannabis in 2022 was recently reinstated to his job with backpay.

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Arkansas Vs US Over Delta-8

Arkansas recently passed legislation to ban cannabis compound delta-8, and other compounds; even when derived from hemp. This led to controversy due to the 2018 Farm Bill, which now involves federal courts. Did Arkansas go too far by including compounds derived from hemp? Read on for more info on this story.

Arkansas ban on hemp-derived delta-8

The current controversy in Arkansas stems from a bill (Act 629) that was signed by Governor Sarah Huckabee Sanders on April 11th of this year. The law is aimed at taming the growing illicit cannabinoids market; by instituting a ban on the production, sale, possession, and transfer of any products with compounds like delta-8, delta-9, delta-10, and so on. The state rescheduled these compounds to Schedule IV, which is the same for standard cannabis. Basically the ban is on anything potentially intoxicating.

According to the legislators who supported the legislation, the ban is necessary because of unregulated stores that sell unregulated products, without checking IDs. There is a logic point, of course; that these stores already function outside of regulation, so instituting regulation isn’t likely to help. I suppose it gives backing for raids, which must be the primary reason for passing such legislation anywhere it does pass…as otherwise it would be expecting non tax-paying businesses, to care about something they don’t care about.

Regardless of the missed logic, the law passed, was signed by the governor in April, and set to go into effect on August 1st. A day before it was scheduled to do so, four lawsuits dropped on the state, by hemp product makers. The four producers are: Bio Gen, out of Fayetteville, Arkansas; Greenbrier, Arkansas’s Drippers Vape & Hemp Relief; Hometown Hero CBD from Austin, Texas; and Smoker Friendly out of Boulder, Colorado.

Arkansas is not a recreational cannabis state

The lawsuits claim that Arkansas’s Act 629, is in violation of the 2018 US Farm Bill, aka the Federal Agriculture Improvement Act of 2018; which legalized industrial hemp, and gave it a new definition that legally separates it from marijuana. The plaintiffs also argue that the law gets in the way of their industry and livelihood, and that it’s in violation of the U.S. Constitution’s commerce and supremacy clauses.

The latter is particularly important as it concerns protections for interstate commerce, and those tasked with bringing products over state lines. This law, according to plaintiff attorney Abtin Mehdizadegan, can now mean a person can face “criminal sanction for products now deemed illegal despite what the federal law says,” according to a thv11 article.

Arkansas defense for delta-8 ban

The 2018 US Farm Bill is a piece of federal legislation that legalized the production, sale, possession, and use of hemp products. It does not legalize any specific hemp or hemp-derived products for medical or other therapeutic use, but it doesn’t specifically disallow them either, creating a little gray area. Add onto that, that most products like delta-8 require some amount of synthetic processing, and the reality becomes that it’s not exactly a legal market.

Having said that, this is not Arkansas’s excuse exactly. The ban is not specifically about synthetics, though the topic is mentioned. Griffin stated “Arkansas recognizes that industrial hemp is a valuable commodity when cultivated as intended. Act 629 does not stifle such production, and instead, protects Arkansas from the adulterated products that result from chemical synthesis.”

The problem with what Arkansas did, is that it went beyond synthetics. It’s one thing to ban the compounds if they come from a marijuana plant, or to tighten the restriction on synthetic processes. It’s even within the limits of legality to really go hard on the .3% THC separating line. But what Arkansas did, is write off tons of products, that if made the correct way, are legal according to US government law. Or at the very least, not illegal. However, since the US government didn’t officially legalize specific products; this case has the potential to put the federal government in quite an odd position.

Arkansas’s Attorney General possibly dug the state in deeper, by actually using the line that the ban should stay, because it was instituted by the state, and that state law wins out over federal law. I repeat that this argument was put forth by Attorney General Tim Griffin in court, according to MJBizDaily.

Arkansas passed a new law that bans delta-8
Arkansas passed a new law that bans delta-8

Griffins is referring to the idea that if something isn’t constitutionally clear, that it can go in either direction; but at no point has this ever meant that a state automatically wins over the federal body. State cannabis legalization measures are based on the lack of constitutional finality on the subject; they did not simply go through because they trump federal policy.

On August 8th, Griffin asked U.S. District Court Judge Billy Roy Wilson to dismiss the lawsuit, in which he made a cheap shot at the plaintiffs for not being of decent standing, and said they didn’t show irreversible harm from the law (which is too newly enacted for such proofs). The case was not dropped; and currently no hearings are scheduled. One could ask what Griffin is really after in this, and what he thinks will really happen. So far, he’s trying to argue that states rights should override federal laws, and he’s been wildly insulting to the plaintiffs in the case.

The only thing Arkansas has to go on for this law, is a stated fear of children getting high. This excuse is made all the time, even while beer cans continue to look like soda, and are sold everywhere. No one dies from cannabis products, with the exception of a few cases where bad additives were used. People do die from opioids, and guess what looks like a little piece of candy… a cute little yellow pill. That the new Arkansas bill says there should be a state of emergency over cannabis products, is an insult to those dealing with real drug danger; like opioids, or alcohol, or cigarette damage.

The case against Arkansas

The case against Arkansas regarding the delta-8 ban, involves several companies, who are together now suing the state. This creates an interesting conundrum for the US government, which they are appealing to. If the plaintiffs get a positive ruling by the court, it would make a ruling on overall legality of certain cannabis products, at least to a degree. This also happened recently when a federal court validated delta-8 products as having a valid trademark, something that an illegal product can’t have.

The federal government has three options. It can uphold its own laws which legalized hemp and hemp-derived compounds. This would work to legalize delta-8 THC, and the other cannabinoids, so long as requirements like not being synthetic, are met. Or, it has the choice of backing Arkansas, in which case it undermines its own laws. Last, it can drop the case, and make no judgement at all; although this too makes a statement in that Arkansas is specifically touting its supremacy over federal law. Really, its very much a catch-22 for the feds.

Arkansas is not the first state to ban compounds like delta-8 THC. Several states have moved to do such things, some with general bans on cannabis in general, and some that have legal markets. Perhaps the biggest issue with what Arkansas did, is that it made the ban without a stipulation for synthetic processing. It just went ahead and banned any of these compounds if they come from hemp, with little-to-no thought about the 2018 Farm Bill, and what it allows.

Legal hemp field post 2018 Farm Bill
Legal hemp field post 2018 Farm Bill

Maybe this case is just a right place at the right time situation. And maybe it goes to show that how a state writes its legislation is important. Overstepping happens, even with legislators trained on writing laws. That, and ego gets involved. Regardless of whether Griffin is agreed with or not on certain points, he was divisive and unnecessarily mean about the plaintiffs in the case; and that is a highly unprofessional, ego-motivated move. And that doesn’t say much for Arkansas right now.


This is certainly a case to watch, because it’s one of those cases that comes along at the right time. The federal government must now make a decision regarding the validity of the Arkansas ban on cannabinoids like delta-8. And in doing so, that decision might force a legal reckoning for certain products. Even throwing out the case makes a statement at this point, as it makes it look like the federal government can’t back up its own laws.

As a final note, I cannot find so much as one place where it says the federal court this case is filed in. This is a bit odd as all articles thus far speak of a federal case, yet there is not one document related. Perhaps the case is private. I note here that I don’t like situations where I’m passing on information that I cannot verify.

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DEA Confirms Delta-8 THC Synthesized from CBD is Federally Illegal

Summary: A letter from 2021 by the U.S. Drug Enforcement Administration’s Drug & Chemical Evaluation Section Chief Terrence Boos reveals that the DEA considers delta-8 THC, synthesized from CBD, to be federally illegal.

Hemp-Derived Delta-8 THC Considered Federally Illegal by DEA

A recently disclosed letter confirms the U.S. Drug Enforcement Administration’s stance that delta-8 THC synthesized from CBD is federally illegal. This perspective encompasses the majority of consumer delta-8 products available in the market.

The letter, penned in 2021 by the DEA’s Drug & Chemical Evaluation Section Chief Terrence Boos, was unveiled last week by attorney Shane Pennington on his “On Drugs” Substack. Boos stated, “Arriving at delta-8-THC by a chemical reaction starting from CBD makes the delta-8-THC synthetic and therefore, not exempted by the [Agriculture Improvement Act]. Any quantity of delta-8-THC obtained by chemical means is a controlled substance.

The Agriculture Improvement Act, commonly referred to as the 2018 Farm Bill, permitted states to launch their hemp programs. This led to a surge in companies selling hemp-derived cannabinoids including hemp-derived THC. Some of these businesses took it a step further by synthesizing hemp-based cannabinoids into more psychoactive substances like delta-8 or even delta-9 THC.

And in Pennsylvania they lail you for selling Delta 8

This letter clearly articulates what many experts have speculated for some time. The DEA, in a presentation on May 4, conveyed its support for classifying all synthetic cannabinoids containing THC, including hemp-derived delta-8 THC, as federally controlled substances. Furthermore, in February, Boos communicated to another attorney that minor cannabinoids, including delta-8 THCO and delta-9 THCO, are illegal since they can only be synthesized and do not occur naturally, as reported by Marijuana Moment.

It’s worth noting that while delta-8 THC does naturally exist in cannabis plants, it’s only in trace amounts. The majority of consumer delta-8 products are synthesized from CBD.


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The legality of hemp is changing…

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AI Disclaimer: This news update was created using AI tools. PsychePen is an AI author who is constantly improving. We appreciate your kindness and understanding as PsychePen continues to learn and develop. Please note that the provided information is derived from various sources and should not be considered as legal, financial, or medical advice.

Delta-8 THC legality is under fire

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Arkansas Hemp Firms File Suit Against Delta-8 THC Ban

A group of hemp businesses has filed a legal action challenging a new Arkansas law that bans hemp-derived psychoactive cannabinoids including delta-8 THC, arguing the statute violates the 2018 Farm Bill’s provisions that legalized hemp agriculture. The lawsuit, which was filed in federal court in Little Rock on Monday by four hemp businesses, seeks an injunction blocking Act 629, a law banning hemp-derived psychoactive cannabinoids that went into effect on August 1.

Act 629 bans the production and sale of products containing delta-8, delta-9 and delta-10 THC and other variations of the cannabinoids inside the state of Arkansas. Such products have been legal under federal law since 2018, when that year’s Farm Bill legalized hemp with less than 0.3% delta-9 THC. Despite their low delta-9 THC content, other psychoactive cannabinoids can be extracted from hemp, and hemp-derived CBD can be processed into psychoactive cannabinoids in a laboratory.

The four plaintiffs in the case include a manufacturer, wholesaler, distributor and retailer of hemp products that would be affected by the ban. They are asking the court to block Act 629, arguing that the statute does not comply with the U.S. Constitution’s commerce and supremacy clauses and is a violation of the 2018 Farm Bill.

“Plaintiffs have been, and will be, harmed by Act 629,” the complaint reads, according to a report from the Northwest Arkansas Democrat-Gazette, “as they are unable to transport in and through Arkansas hemp-derived cannabinoid products that have been declared legal under federal law.”

Last year, the federal Ninth Circuit Court of Appeals issued a ruling in a trademark case in which the legality of delta-8 THC was a key factor. The court confirmed that delta-8 THC is legal under the 2018 Farm Bill.

“Regardless of the wisdom of legalizing delta-8 THC products, this Court will not substitute its own policy judgment for that of Congress,” the appellate court wrote in its ruling. “If … Congress inadvertently created a loophole legalizing vaping products containing delta-8 THC, then it is for Congress to fix its mistake.”

The plaintiffs in the case are Bio Gen, LLC of Fayetteville; Drippers Vape Shop, LLC of Greenbrier; The Cigarette Store LLC of Colorado, doing business as Smoker Friendly; and Sky Marketing Corporation of Texas doing business as Hometown Hero. Drippers is a retailer of hemp products, including non-psychoactive CBD as well as hemp-derived psychoactive substances Delta-8 and Delta-9 THC, and has stores in the communities of Greenbrier, Cabot, Hot Springs, El Dorado and Benton, according to a report from the Arkansas Times.

The named defendants in the lawsuit are the state of Arkansas, Governor Sarah Huckabee Sanders, Attorney General Tim Griffin, the Arkansas Department of Finance and Administration, the Arkansas Tobacco Control Board, the Arkansas Department of Agriculture, the State Plant Board and the prosecuting attorneys of the state’s 28 judicial circuits.

Abtin Mehdizadegan, the lead attorney for the plaintiffs, says that his clients tried to avoid legal action before Act 629 was signed into law.

“Our suit asks the federal court in the Eastern District of Arkansas to enjoin the entirety of Act 629 because it unconstitutionally narrowed the definition of hemp-derived products in violation of the 2018 Farm Bill and impermissibly restricted the transportation and shipment of these products,” Mehdizadegan wrote in an email. “Before the bill was signed into law, we had lengthy dialogues with the defendants during the 2023 legislative session as the bill was making its way through the legislative process.” 

“We also testified before a House Subcommittee to explain the constitutional infirmities in the initial draft of Act 629,” Mehdizadegan continued. “At the same time, we remain ready and willing to continue those discussions and would invite the State to meet us at the table to arrive at a sensible resolution. We do not oppose all forms of regulation and would support sensible policies that appropriately treat hemp-derived products for what they are: as an agricultural commodity.”

Cynthia Cabrera, chief strategy officer at Hometown Hero CBD, one of the plaintiffs in the case, said that Arkansas’ ban on hemp-derived cannabinoids would harm small businesses and hamper the growth of the state’s hemp industry.

“Mom-and-pop farmers, manufacturers, and retailers have put their life blood into building legacy businesses around a federally legal product,” Cabrera said in a statement to High Times. “Businesses like Hometown Hero invested in Arkansas in part relying on the state’s declared public policy to position itself at ‘the forefront of industrial hemp production, development, and commercialization.’ And overnight, Act 629 turned farmers into felons and retailers into drug dealers—all in violation of federal law. Ultimately, we would like to see reasonable regulation that allows businesses to grow and thrive while allowing adult consumers access to safe, legal hemp-derived products.”

Act 629 also includes provisions to regulate psychoactive hemp-derived cannabinoids in the event that the ban is struck down by the courts. Under the regulatory plan, wholesalers, distributors and retailers of the products would be required to obtain a permit from Arkansas Tobacco Control at a cost of $5,000 per year. Psychoactive cannabinoids derived from hemp would be legal, but the statute would prohibit mixing the compounds with additives such as liquids, sweeteners or other non-hemp products. The plaintiffs of the lawsuit are also challenging the regulatory plan, arguing that the rules put unreasonable burdens on them and amount to a “regulatory taking” of their legal property that makes it unusable.

The post Arkansas Hemp Firms File Suit Against Delta-8 THC Ban appeared first on High Times.

Cannabis at California’s State Fair

Pinch me, please! This was the second year of the Cannabis Exhibition at the California State Fair at Cal Expo in Sacramento, and I still have a hard time believing it really happened.

Swami and I were honored once again to be ambassadors for this very special event, along with 18 others from various sectors of the industry. The fair lasted 17 days, and each of the three weekends was packed with special cannabis events (although no cannabis was actually allowed on site). While cannabis remains classified as a “product” as opposed to a “crop” (go figure), it seems appropriate that it should be at the fair, alongside wine, vegetables and fruits. Oh, and the funnel cakes and corn dogs, too.

The Cannabis Exhibition is all about educating the canna-curious and awarding the canna-cultivators. According to event producer James Leitz of Cultivar Brands, there were 250 entries into the competition this year, and 63 winners were awarded in the heart-warming ceremony held the first weekend. Many of the farmers were on site to accept, some even asking to have the medals placed around their necks, like true Olympians. “They wanted their Golden Bears,” Leitz said, referring to the trophies of the Bear, which has been the fair logo since it began 168 years ago.

Nikki and Swami with the iconic California State Fair’s Golden Bear.

Cannabis’ Time to Shine

California is the first State in the Union to sanction a cannabis competition and exhibit. The 7,500-square-foot exhibition hall was indicative of their commitment to honoring the plant. The programming on the main stage was varied and informative, featuring everything from wellness panels, storytelling, organic cultivation guidelines, indigenous farming and even a Sunday morning meditation guided by Swami Chaitanya. There truly was something for everyone, from newbies to well-seasoned growers.

The second weekend celebrated women in cannabis, which was super special. Produced by Mskindness Ramirez and a crew of awesome women in weed, the Sunday presentations included panels on the challenges and benefits of using cannabis during motherhood, as well as other life stages. They also published “The Ethical Consumer’s Green Book,” a handy guide full of information for interested consumers.

Keiko Beattie speaking on the Women Weed Wellness panel as part of the Cannabis Exhibition.

The final week focused on Veterans and treating their traumas with cannabis as well as presentations by the Department of Cannabis Control (DCC) about the legality of cannabis in California. It all wrapped up Sunday, July 30 with demos and talks about making edibles, canna-beverages and how to pair comestibles and cannabis.

In 2022, James Leitz, along with Brian Applegarth and Caitlin Tamony, marketing director at Cultivar, had the vision and the connections to make the exposition happen. While this year, Applegarth has chosen to focus on expanding cannabis tourism; he remains a Cannabis Ambassador at the State Fair. Leitz and Tamony carried on and did an amazing job this year creating even more informative displays that ranged from the history of cannabis to photos of legacy growers and types of consumption. There were even some hemp plants on display behind a glass wall.

One of the most fun displays was set up by the DCC and featured a large wall that said, “Where Do You Buy Your Weed?” Visitors were given sticky notes to stick their answers up there, some of which were pretty funny. My personal favorite: “I ain’t no snitch.”

Cannabis Exhibition California State Fair
“I ain’t no snitch.”

“The California Cannabis Exhibit has been a wonderful opportunity to interact with the public about cannabis. Fairgoers, and our staff, have enjoyed our ‘Where do you buy your weed?’ display,” shared Nina Lemke, the DCC’s manager of outreach and education. “The seemingly simple question has helped start discussions about cannabis safety while also inspiring friendly debates on best licensed retail stores. It’s been a very positive experience for everyone.”  

This was the DCC’s first year at the fair and it felt like such a positive step, as they’ve been very supportive. “We chose to align with the various DCC license types to create our categories for judging,” Leitz says. “Since the fair is all about education, we wanted to keep the awards based on science at this point, as opposed to people actually smoking it to judge. It’s time for cannabis to join other commodities and shine.”

Cannabis Exhibition California State Fair
Honoring California’s legacy and craft community at the Cannabis Exhibition.

Cannabis, Corn Dogs and Cotton Candy

It’s also of interest that many of this year’s winners were also Emerald Cup winners, although The Cup uses a different technique and definitely has humans judging, rather than basing the awards on the highest lab numbers. Alec Dixon of SC Labs handled the lab testing on all entries and, as he always says, “High terpene numbers equal quality craftsmanship.” Not only terpenes were judged, however, as awards were also given to the highest-scoring THCa, CBDa and CBGa cannabinoids. The best numbers in six primary terpenes were also awarded. The three divisions, classified by their light source, were Outdoor, Mixed Light and Indoor Grown, and each section received awards in all categories, both gold and silver levels. To feature the seal of a State fair winner on your product carries a lot of weight.

Visitors were funneled first through the educational exhibits and award-winner displays, into the stage and presentations area and then to several booths featuring brands, industry organizations and farmers to answer your questions. “Our docents are the farmers,” Leitz proudly announced.

Award-winners proudly displayed at the Cannabis. Exhibition

To whet your whistle, a special slushie stand offered refreshing colorful CBD-infused beverages which were most welcome considering the thermometer outside rose as high as 106 degrees on some days. Luckily, the hall was nicely air-conditioned. Randy Reed of Scientific Solutions, along with his wife Angelica and their wonderful dog Cami, were busy the whole time making the drinks for interested consumers, many of whom had never tried any type of hemp or cannabis product before. “I tell them it’s like taking a vitamin for your cannabinoid system, and once they try it and get relief, they always come back for more,” Reed said.

The last booth, just two spaces away from the DCC, was the very popular Humble Root cannabis delivery company. Located in Sacramento, they were brought on to run the exclusive State Fair delivery service. The way it worked was customers would check out their menu at the booth, register and then place an order. Next, they’d go outside to meet and pay the driver outside the main entrance to the Fair.

Cannabis Exhibition California State Fair
The day’s most popular tee-shirt: Cannabis, Corn Dogs & Cotton Candy.

Irvin Hernandez and Colin Schmidt were running the booth and said that the most popular items were the edibles, although they also featured winning State Fair flowers from this year’s competition on their menu. It was all “easy peasy” and 100% legit. “We’re following all the rules to set a good example,” Irvin explained. Mental note for next year: You can get more than corn dogs and cotton candy at the State Fair!

Leitz and Tamony did a great job of laying out the exhibit. “Once they experience all the education etcetera, they exit through the gift shop,” Leitz laughed. Merch sales are a big deal at the State Fair and their most popular T-shirt says, “Cannabis, Corn Dogs & Cotton Candy.” Also available were rolling trays, grinders and even a bong with the State fair logo on them—how far we have come!

I admit to seeing very little at the rest of the fair, which stretches across 350 acres, including all the animals, display gardens, amusement park rides, many exhibition halls, sky tram and more. The Cannabis Exhibition was captivating and made me proud to be an Ambassador. This is yet another step—and a big one—on our path to full acceptance.

The post Cannabis at California’s State Fair appeared first on Cannabis Now.

What Is Delta 9P? Everything You Need To Know

You may have noticed that the hemp industry has been all about super potent cannabinoids in the last year or so. And, with growing demand for hemp products that can get us unbelievably high, the industry has developed new and highly advanced techniques for taking naturally occurring cannabinoids and making them even stronger.

Case in point: Delta 9 and Delta 9P products. This rarer cannabinoid is new to the market, and you aren’t going to find it in every store just yet. But, its popularity is growing fast, because it offers a memorable high that appeals to anyone with a substantial THC tolerance. Let’s share everything you need to know about this cannabinoid so you can decide if it’s worth trying. But, as a spoiler alert, we want to mention that if you’re ready for one of the most powerful highs of your life, you can try Delta 9P products 25% off using the code HIGHTIMES25 here.

Delta 9P: What You Should Know

Delta 9P is an extremely new development as a type of THC-P, as there is Delta 9 THC-P and Delta 8 THC-P. Delta 8 THC-P is very strong, while Delta 9 THC-P is on a whole new playing field. With a feeling around 35x stronger than regular Delta 9 THC.

What Kind of High Will I Get From Delta 9P?

If you’ve been keeping up with the hemp industry for a while, then you won’t be surprised when we say that Delta 9P and Delta 9P vapes, being such a brand new addition to the market, is lacking in research, as well as anecdotal information about its effects. It’s not a cannabinoid that you can easily find just yet, like we said before.  

Because of that, you’re going to have a hard time finding consistent info about what to expect from its high. To complicate matters, we already know that with a lot of these newer cannabinoids, results can vary a bit from one person to the next because of the way in which they interact with different cannabinoid receptors in the brain.

Basically, what we can say is that Delta 9P is going to give you an unbelievably strong psychoactive effect.  It’s said to be more intoxicating than Delta 8 THC-P, as we said earlier, and the high is probably very euphoric yet calming, as that’s something we see consistently with THC-P.

Does Delta 9P Have Any Benefits?

Again, we really don’t have enough information to know what kinds of benefits Delta 9P has in store. This just isn’t a cannabinoid that has undergone extensive medical research, like cannabinoids that have been around for decades, such as CBD or Delta 9. But, once again, because Delta 9P is essentially the strongest version of THC-P, it’s likely that it delivers the same benefits found in both of these cannabinoids, which include:

  • Relief from inflammation
  • Relief from physical discomfort
  • Relief from stress/anxiety
  • Mood-boosting effects
  • Neurological regulation
  • Relief from nausea
  • Help with sleep
  • Improvement in appetite
Courtesy Binoid

Of course, such an intoxicating cannabinoid would leave a lot of people assuming that it’s not fully legal. But, at the end of the day, Delta 9P is fully compliant with the federal Farm Bill, which allows all hemp products to be sold legally as long as they contain no more than 0.3% Delta 9 THC. Delta 9P is therefore totally unrestricted, and can be enjoyed legally – under federal law, that is.

As many know, a number of states have banned THC isomers, meaning that psychoactive cannabinoids cannot be sold. So, Delta 9P is illegal in:

  • Alaska
  • Arizona
  • Arkansas
  • Colorado
  • Delaware
  • Hawaii
  • Idaho
  • Iowa
  • Maryland
  • Mississippi
  • Montana
  • Nevada
  • New York
  • North Dakota
  • Oregon
  • Rhode Island
  • Utah
  • Vermont
  • Washington

Where Can I Buy Delta 9P?

Great question – Delta 9P and Delta 9P vapes are only slowly making its way into stores, and for now, you’re far more likely to find it in vape form than any other product type. As always, you want to make sure you’re buying from a reputable company, and that you can easily access lab reports on their website to verify the authenticity, safety, purity, and potency of the product.

One brand that’s introducing their Delta 9P to the public is Binoid, as they’re developing Delta 9P vapes in a great choice of strains.  We recommend their products, as the brand has maintained a stellar reputation over the years for selling top-quality, safe, and highly effective formulas, made without unwanted additives, and consistently sold fresh for maximum positive impact. Currently Binoid offers 6 brand new Delta 9P strains including Tropical Zkittlez, Alaskan Lights, and Desert Diesel, Vice City, Space Mountain, and Hot Lava.. You can get right on their website for an amazing price.

In fact, Binoid is one of the first brands to carry Delta 9P products and vapes that are extremely potent and enjoyable. On top of their amazing product, they have amazing customer service, Delta 9P vape prices are the lowest we have seen, and just overall one of the best places to buy Delta 9P online.

Courtesy Binoid

Delta 9P: Not for the Faint of Heart, But Highly Rewarding

It’s likely that Delta 9P is one of the strongest cannabinoids you’ll ever have the pleasure of trying, in terms of its ‘high’. And, while that may not be for everyone, there’s a growing number of enthusiasts who are seeking out just that. For now, it’s not too easy to find, but one company that promises top-quality Delta 9P is Binoid, with exquisitely crafted vapes made from the purest Delta 9P distillate and freshest terpenes around. 

Is Delta 9P Safe?

It’s important to note that Delta 9P hasn’t been around for nearly a long enough time for us to be able to talk about its potential therapeutic uses as determined through clinical trials and research. Since Delta 9P is totally new, there just isn’t any research out there about it. And, with an array of cannabinoids being unearthed and developed in the last few years, you can imagine that cannabis researchers have their hands full, and Delta 9P is not the first in line to explore in clinical settings.

It’s safe to assume that Delta 9P offers the same properties as THC-P, only with harder-hitting and longer-lasting effects as an added bonus. So, you can expect Delta 9P to offer relief from physical discomfort and inflammation, along with help regarding nausea and appetite, not to mention very enjoyable effects when it comes to mood.

Courtesy Binoid

What Else is Delta 9P Good For?

We always want to be careful to talk about benefits of any cannabinoid without clinical studies that we can refer to, for ethical reasons. And, there are no papers that have been published in scientific journals about the properties and effects of Delta 9P, because the cannabinoid just came out, and there hasn’t been time for proper analysis by cannabis researchers.

Still, it’s likely that Delta 9P offers benefits similar to those of Delta 9P, like potential mood improvements, appetite enhancement and more. 

Delta 9P Dosage and Dosing Guide

As we learn more about Delta 9P, we’ll have much more specific dosing guidelines available.  What we can say is that since the cannabinoid is so potent, you don’t want to take as many milligrams in one sitting as you would a milder cannabinoid like Delta 8. Because Delta 9P is so strong, doses look to be small amounts, but that is because of how strong the compound is.

Comparing Delta 9P potency to other cannabinoids, however, we can offer a general idea of how much you should take whether you’re a beginner, intermediate, or advanced user, regardless of the product type that’s available above:

  • Beginners Delta 9P dosing: 1mg-3mg
  • Intermediate Delta 9P Users dosing: 3mg-5mg
  • Advanced Delta 9P Users dosing: 5mg+   

Delta 9P is the strongest cannabinoid in hemp with a strength 35x stronger than regular Delta 9 THC. This means that all products using Delta 9P vapes and gummies will be extremely potent, and small MG’s are necessary.

Will Delta 9P Fail A Drug Test?

As a rule of thumb, any time you encounter a cannabinoid, you should assume that it puts you at risk of failing a drug test. Why? Because all THC-based cannabinoids are metabolized by an enzyme called THC-COOH, which is what standard drug tests are seeking to identify in a person’s urine.

Because Delta 9P and Delta 9P products are particularly potent and are the stronger form of Delta 9 THCP, there’s good reason to believe that it’s very likely to fail a drug test. 

Delta 9P Has Arrived at Binoid!

Delta 9P and Delta 9P products, being so powerful, are going to be a cannabinoid that Binoid customers are looking forward to trying. This unique cannabinoid blend really does stand out from the rest by promising effects even stronger than those of Delta 8 THC-P.

Check out Binoid Delta 9P products and vapes with 25% off using the code HIGHTIMES25 if you want to try the strongest cannabinoid hemp has to offer. With amazing prices, trusted products, free shipping and 24/7 customer service, you cannot go wrong trying Binoid!

Courtesy Binoid

The post What Is Delta 9P? Everything You Need To Know appeared first on High Times.