Cannabichromene – How CBC Interacts With Our Brain’s “Bliss” Molecule to Target Depression

An average of 9.5% of American adults ages 18 and over will suffer from an ongoing depressive illness every year – that’s roughly 17 million people. For many, finding relief is a daily struggle between managing symptoms, avoiding triggers, and trying to find a treatment plan that actually works – the latter often proving to be more difficult than most would expect. The reason for that is simple: pharmaceutical antidepressants just aren’t that effective. Natural compounds that interact with existing receptors in our bodies… that is what really works, and that is what certain cannabinoids like Cannabichromene (CBC) have to offer.

Are you a cannabis aficionado who would like to learn more about cannabichromene, as will as other cannabinoids and all aspects of this incredible plant? If so, make sure to subscribe to The CBD Flowers Weekly Newsletter for the best of the best that this industry has to offer, as well as access to exclusive deals on flowers and other products. Or you can check out the Delta 8 Weekly Newsletter for the best deals on Delta 8 THC.

Wholesales: Click HERE for Delta 8 & Delta 10 THC wholesale opportunities


What is Cannabichromene (CBC)?

Although much of the global discourse regarding cannabis is focused on THC and CBD, cannabichromene (CBC) is next in line as the third most prominent compound in the plant, and of equal importance therapeutically. In most strains (both marijuana and hemp), CBC ranges from 0.3% to 0.9% of the total plant constituents. Just like other cannabinoids, CBC starts out as a plant acid – cannabichromenic acid to be specific – and eventually drops the carboxyl acid group becoming just cannabichromene.

CBC is non-psychoactive and interacts with the endocannabinoid system differently than both THC and CBD. THC binds directly with both the CB1 and CB2 receptors, and CBD interacts indirectly to these receptors via secondary pathways. CBC, however, is an agonist of only the CB2 receptors, which play a vital role in immune function, pain management, inflammation, and overall homeostasis.

Researchers have been looking at CBC for a few decades now, with studies dating back to 1981. In one of the earlier studies, the anti-inflammatory, antibacterial, and antifungal properties of CBC were put to the test. It was discovered that CBC was more powerful than phenylbutazone (an NSAID anti-inflammatory/pain medication) at controlling inflammation. It was also found to be a potent antibacterial and a moderately effective antifungal treatment as well.


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Limitless Delta 8 CBC Vape Cartridge Bundle

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Fast forward to a 2006 study, in which numerous cannabinoids were examined to see if they could be used to shrink tumors. Among the cannabinoids tested was cannabichromene, and it scored equally well as THC and CBD at suppressing tumor growth in the animal subjects. 

And finally, in this 2010 scientific study, the anti-depressant activity of CBC and other cannabinoids was tested on mice. In one part of the study – a forced swim – CBC, CBD and Delta 9 THC all showed significant anti-depressant effects. In the second part of the study – a tail suspension test – CBC and Delta-9-THC were said to have the most significant mood-elevating properties compared to other cannabinoids as well as the pharmaceutical antidepressants they were tested against.

Additional studies over the years echoed these findings, and also found that CBC produced an antinociceptive response that helped control pain, minimize digestive issues, and offered neuroprotective qualities. As with other cannabis compounds, research on the full potential of cannabichromene is still ongoing, but it has shown potential as both a standalone treatment and working synergistically with other cannabinoids.

Anandamide and Homeostasis – The Bliss Molecule

When it comes to happiness, the majority of it is situational; but according to newer global studies, the levels of happiness one feels on a regular basis can have some genetic components as well. If you know any people that seem just naturally happier than others, it might be because they have higher levels of anandamide in their brains.

Anandamide (N-arachidonoylethanolamine) is first endocannabinoid, discovered and isolated by Lumír Hanuš (Israel) and William Devane (United States) in 1992. The name comes from the Sanskrit word “ananda,” translating to “internal bliss, joy, or delight.” Anandamide is a fatty acid neurotransmitter that activates the same receptors as THC.

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Normally, anandamide is broken down by the fatty acid amino hydrolase enzyme (FAAH), at which point it is no longer in the body and thus, no more blissful effects are felt from this compound. Some people and animals produce less FAAH enzymes, and these people report feeling overall happier, experiencing less fear and anxiety than those who produce more FAAH. In addition to mental health, anandamide has been found to positively impact fertility and inhibit the growth of breast cancer tumors.

People whose bodies break down anandamide faster, can benefit greatly from supplementing with phytocannabinoids (cannabinoids created by plants); but the key is knowing which ones most closely mimic the bliss molecule’s effects. CBC, CBD, and THC all offer positive effects, but due to CBC’s affinity for the CB2 receptor, it seems to work best for elevating mood without producing any unwanted psychoactive side effects.

CBC’s Effect on Anandamide

The only reason cannabis actually works and has an effect on us at all is because of the Endocannabinoid System (ECS), which is responsible for numerous different psychological and physiological functions. Researchers have discovered two different endocannabinoids so far, 2-arachidonoylglycerol (2-AG) and anandamide (AEA).

In addition to the naturally produced cannabinoids, there is also a large web of receptors that allow AEA and 2-AG to function the way they do. The two receptors that have been studied most extensively are CB1 and CB2. Cannabinoid receptors sit on the surface of cells and monitor conditions on the outside. Once they sense changes and the body begins falling out of a state of homeostasis, they signal the appropriate cellular response to restore balance.

When we don’t produce enough endocannabinoids to complete this cycle, our bodies become unstable and no longer perform optimally, leading to the onset of numerous different diseases and disorders. This is where supplementing with the phytocannabinoids found in cannabis becomes extremely beneficial.

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All of the cannabinoids studied have their place, but cannabichromene was shown to have the strongest antidepressant effects when compared to THC, CBD, and CBG. Because CBC has such strong effects on a group of ion channels located on the plasma membrane, known as the transient receptor potential (TRP) channels, it also has strong effects on anandamide and dopamine. When CBC turns on these receptors, increased levels of the body’s all-natural endocannabinoids like anandamide are released.

One of the greatest medicinal qualities of CBC is that, since it does not interact with the CB1 receptors like THC, it works efficiently at elevating the mood without any intoxicating, psychoactive effects.  

Dangers of Pharmaceutical Antidepressants

Depressive disorders are on the rise, they have been for years, but we’ve seen an even sharper uptick of cases since the COVID-19 pandemic began. By the age of 19, roughly 25% of adolescents have experienced a depressive or major anxious episode, and that number jumps sharply to 53% by 30 years of age. Recent studies show that a growing number of young adults are using antidepressants, which can be beneficial for the mental state but, like all medications, come with a slew of unwanted side effects.

When it comes to the exact figures of how many Americans are taking antidepressant medication on a regular basis, here are the estimates: 4% of children 6-12 years of age, 7% of adolescents 12-18 years of age, and 10-22% of adults (a number that, as explained above, increased with age).  

CBC Distillate 99%

CBC Distillate 99%
CBC Distillate 99%

Common antidepressant side effects:

  • headaches
  • dry mouth
  • blurred vision
  • digestive issues, such as stomach upset, nausea, and constipation
  • dizziness
  • drowsiness
  • trouble sleeping
  • memory problems
  • fatigue
  • weight gain
  • sexual problems such as low sex drive, erectile dysfunction, or ejaculation problems
  • trouble urinating
  • fast heart rate
  • sweating
  • increased risk of suicidal thoughts and actions (especially in users under the age of 25)

To add to the dilemma, newer research and scientific reviews have found that, on average, antidepressants in children and young adults only led to very miniscule psychological improvements when compared to placebo treatments. This was especially true for children and adolescents, who face the greatest risks from taking these medications.

Also keep in mind that physical health is often the catalyst that sets mental health conditions in motion, so it would be a bit of a catch 22 to take antidepressants for depression, and end up with some type of physical ailment that leaves you feeling anxious and depressed all over again.

Final Thoughts

Depression affects millions of people, here in the U.S. and globally. Throughout the world, one in four people suffer from mental and/or neurological disorders at some point in their lives. Wouldn’t it be amazing to have a therapeutic solution that was safe, natural, and actually worked? Cannabis science is still in its infancy but the research we do have shows that it certainly is promising, and in some studies, cannabinoids like cannabichromene performed better than prescription medication (thanks to the presence of anandamide in our endocannabinoid systems). It says a lot and really emphasizes the need for more research and better regulations, especially in the field of mental health.

Hello.. Welcome to CBDtesters.co, the #1 spot for the most relevant cannabis-related news from around the world. Give us a read-thru every day to stay abreast of the quickly-changing world of legal marijuana, and sign up to receive our newsletter, so you always know what’s going on.

The post Cannabichromene – How CBC Interacts With Our Brain’s “Bliss” Molecule to Target Depression appeared first on CBD Testers.

How a Rare Cannabinoid Interacts With Our Brain’s “Bliss” Molecule to Target Depression

An average of 9.5% of American adults ages 18 and over will suffer from an ongoing depressive illness every year – that’s roughly 17 million people. For many, finding relief is a daily struggle between managing symptoms, avoiding triggers, and trying to find a treatment plan that actually works – the latter often proving to be more difficult than most would expect. The reason for that is simple: pharmaceutical antidepressants just aren’t that effective. Natural compounds that interact with existing receptors in our bodies… that is what really works, and that is what certain cannabinoids like Cannabichromene (CBC) have to offer.

Are you a cannabis aficionado who would like to learn more about cannabichromene, as will as other cannabinoids and all aspects of this incredible plant? If so, make sure to subscribe to The CBD Flowers Weekly Newsletter for the best of the best that this industry has to offer, as well as access to exclusive deals on flowers and other products. Or you can check out the Delta 8 Weekly Newsletter for the best deals on Delta 8 THC.


What is Cannabichromene (CBC)?

Although much of the global discourse regarding cannabis is focused on THC and CBD, cannabichromene (CBC) is next in line as the third most prominent compound in the plant, and of equal importance therapeutically. In most strains (both marijuana and hemp), CBC ranges from 0.3% to 0.9% of the total plant constituents. Just like other cannabinoids, CBC starts out as a plant acid – cannabichromenic acid to be specific – and eventually drops the carboxyl acid group becoming just cannabichromene.

CBC is non-psychoactive and interacts with the endocannabinoid system differently than both THC and CBD. THC binds directly with both the CB1 and CB2 receptors, and CBD interacts indirectly to these receptors via secondary pathways. CBC, however, is an agonist of only the CB2 receptors, which play a vital role in immune function, pain management, inflammation, and overall homeostasis.

Researchers have been looking at CBC for a few decades now, with studies dating back to 1981. In one of the earlier studies, the anti-inflammatory, antibacterial, and antifungal properties of CBC were put to the test. It was discovered that CBC was more powerful than phenylbutazone (an NSAID anti-inflammatory/pain medication) at controlling inflammation. It was also found to be a potent antibacterial and a moderately effective antifungal treatment as well.


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Limitless Delta 8 CBC Vape Cartridge Bundle

Limitless Delta 8 CBC Vape Cartridge Bundle

Fast forward to a 2006 study, in which numerous cannabinoids were examined to see if they could be used to shrink tumors. Among the cannabinoids tested was cannabichromene, and it scored equally well as THC and CBD at suppressing tumor growth in the animal subjects. 

And finally, in this 2010 scientific study, the anti-depressant activity of CBC and other cannabinoids was tested on mice. In one part of the study – a forced swim – CBC, CBD and Delta 9 THC all showed significant anti-depressant effects. In the second part of the study – a tail suspension test – CBC and Delta-9-THC were said to have the most significant mood-elevating properties compared to other cannabinoids as well as the pharmaceutical antidepressants they were tested against.

Additional studies over the years echoed these findings, and also found that CBC produced an antinociceptive response that helped control pain, minimize digestive issues, and offered neuroprotective qualities. As with other cannabis compounds, research on the full potential of cannabichromene is still ongoing, but it has shown potential as both a standalone treatment and working synergistically with other cannabinoids.

Anandamide and Homeostasis – The Bliss Molecule

When it comes to happiness, the majority of it is situational; but according to newer global studies, the levels of happiness one feels on a regular basis can have some genetic components as well. If you know any people that seem just naturally happier than others, it might be because they have higher levels of anandamide in their brains.

Anandamide (N-arachidonoylethanolamine) is first endocannabinoid, discovered and isolated by Lumír Hanuš (Israel) and William Devane (United States) in 1992. The name comes from the Sanskrit word “ananda,” translating to “internal bliss, joy, or delight.” Anandamide is a fatty acid neurotransmitter that activates the same receptors as THC.

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NEW: Delta-10 THC Tincture
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Normally, anandamide is broken down by the fatty acid amino hydrolase enzyme (FAAH), at which point it is no longer in the body and thus, no more blissful effects are felt from this compound. Some people and animals produce less FAAH enzymes, and these people report feeling overall happier, experiencing less fear and anxiety than those who produce more FAAH. In addition to mental health, anandamide has been found to positively impact fertility and inhibit the growth of breast cancer tumors.

People whose bodies break down anandamide faster, can benefit greatly from supplementing with phytocannabinoids (cannabinoids created by plants); but the key is knowing which ones most closely mimic the bliss molecule’s effects. CBC, CBD, and THC all offer positive effects, but due to CBC’s affinity for the CB2 receptor, it seems to work best for elevating mood without producing any unwanted psychoactive side effects.

CBC’s Effect on Anandamide

The only reason cannabis actually works and has an effect on us at all is because of the Endocannabinoid System (ECS), which is responsible for numerous different psychological and physiological functions. Researchers have discovered two different endocannabinoids so far, 2-arachidonoylglycerol (2-AG) and anandamide (AEA).

In addition to the naturally produced cannabinoids, there is also a large web of receptors that allow AEA and 2-AG to function the way they do. The two receptors that have been studied most extensively are CB1 and CB2. Cannabinoid receptors sit on the surface of cells and monitor conditions on the outside. Once they sense changes and the body begins falling out of a state of homeostasis, they signal the appropriate cellular response to restore balance.

When we don’t produce enough endocannabinoids to complete this cycle, our bodies become unstable and no longer perform optimally, leading to the onset of numerous different diseases and disorders. This is where supplementing with the phytocannabinoids found in cannabis becomes extremely beneficial.

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Delta 8 Vape Cartridges – Premium Bundle

Delta 8 Premium Vape Carts - Coupon: Delta25
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All of the cannabinoids studied have their place, but cannabichromene was shown to have the strongest antidepressant effects when compared to THC, CBD, and CBG. Because CBC has such strong effects on a group of ion channels located on the plasma membrane, known as the transient receptor potential (TRP) channels, it also has strong effects on anandamide and dopamine. When CBC turns on these receptors, increased levels of the body’s all-natural endocannabinoids like anandamide are released.

One of the greatest medicinal qualities of CBC is that, since it does not interact with the CB1 receptors like THC, it works efficiently at elevating the mood without any intoxicating, psychoactive effects.  

Dangers of Pharmaceutical Antidepressants

Depressive disorders are on the rise, they have been for years, but we’ve seen an even sharper uptick of cases since the COVID-19 pandemic began. By the age of 19, roughly 25% of adolescents have experienced a depressive or major anxious episode, and that number jumps sharply to 53% by 30 years of age. Recent studies show that a growing number of young adults are using antidepressants, which can be beneficial for the mental state but, like all medications, come with a slew of unwanted side effects.

When it comes to the exact figures of how many Americans are taking antidepressant medication on a regular basis, here are the estimates: 4% of children 6-12 years of age, 7% of adolescents 12-18 years of age, and 10-22% of adults (a number that, as explained above, increased with age).  

CBC Distillate 99%

CBC Distillate 99%
CBC Distillate 99%

Common antidepressant side effects:

  • headaches
  • dry mouth
  • blurred vision
  • digestive issues, such as stomach upset, nausea, and constipation
  • dizziness
  • drowsiness
  • trouble sleeping
  • memory problems
  • fatigue
  • weight gain
  • sexual problems such as low sex drive, erectile dysfunction, or ejaculation problems
  • trouble urinating
  • fast heart rate
  • sweating
  • increased risk of suicidal thoughts and actions (especially in users under the age of 25)

To add to the dilemma, newer research and scientific reviews have found that, on average, antidepressants in children and young adults only led to very miniscule psychological improvements when compared to placebo treatments. This was especially true for children and adolescents, who face the greatest risks from taking these medications.

Also keep in mind that physical health is often the catalyst that sets mental health conditions in motion, so it would be a bit of a catch 22 to take antidepressants for depression, and end up with some type of physical ailment that leaves you feeling anxious and depressed all over again.

Final Thoughts

Depression affects millions of people, here in the U.S. and globally. Throughout the world, one in four people suffer from mental and/or neurological disorders at some point in their lives. Wouldn’t it be amazing to have a therapeutic solution that was safe, natural, and actually worked? Cannabis science is still in its infancy but the research we do have shows that it certainly is promising, and in some studies, cannabinoids like cannabichromene performed better than prescription medication (thanks to the presence of anandamide in our endocannabinoid systems). It says a lot and really emphasizes the need for more research and better regulations, especially in the field of mental health.

Hello.. Welcome to CBDtesters.co, the #1 spot for the most relevant cannabis-related news from around the world. Give us a read-thru every day to stay abreast of the quickly-changing world of legal marijuana, and sign up to receive our newsletter, so you always know what’s going on.

The post How a Rare Cannabinoid Interacts With Our Brain’s “Bliss” Molecule to Target Depression appeared first on CBD Testers.

The Endocannabinoid System Explained – Why Cannabis Is Good for Our Bodies

Cannabis has been pinned as a treatment option for many different disorders lately, many of them seeming completely unrelated. Everything from physical pain to mental disorders and even cancer are said to respond to cannabinoid treatments, but how exactly is that possible?

When you first start hearing about all the different conditions that medicinal cannabis is being used for these days, it almost seems like a gimmick to legalize. Can one plant, not to mention it’s a plant that gets you high, seriously have so many therapeutic benefits? Although it may seem like a stretch, if you have an understanding of the Endocannabinoid System, it makes a lot more sense why cannabis actually works so well in the human body.

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What is the Endocannabinoid System?

The only reason cannabis actually works and has an effect on us at all is because of the Endocannabinoid System (ECS). Simply put, the ECS is a network of receptors that exists in the bodies of all mammals, plus the endocannabinoids that bind to them. As a whole, the ECS regulates numerous different functions and processes in our bodies and maintains internal balance and homeostasis.

Researchers have discovered two different endocannabinoids so far, 2-arachidonoylglycerol (2-AG) and anandamide (AEA). 2-AG is made from omega-6 fatty acids and is present in fairly high levels in the central nervous system, but it has also been detected in human (and bovine) milk. 2-AG is a full agonist of both the CB1 and CB2 receptors, but it has a stronger influence over the CB2 receptor. Because of this, 2-AG is thought to have a substantial impact on the immune system.

Anandamide (AEA), also commonly referred to as the “bliss molecule”, is believed to play a major role in the in all of our basic daily physiological functions including sleep/wake cycles, appetite, mood, and even fertility; but we’ll get more in-depth on the benefits of this cannabinoid a bit later.

In addition to the naturally produced cannabinoids, there is also a large web of receptors that allow AEA and 2-AG to function the way they do. The two receptors that have been studied most extensively are CB1 and CB2. Cannabinoid receptors sit on the surface of cells and monitor conditions on the outside. Once they sense changing conditions and the body falling out of a state of homeostasis, they signal the appropriate cellular response to restore balance.

Anandamide: The Bliss Molecule

Although there are two known endocannabinoids, one is by far more prominent in research and literature: Anandamide (AEA). The reason AEA is known as the Bliss Molecule is because of the role in plays in balancing our body functions and elevating our moods. Multiple studies have been conducted on the benefits of being exposed to varying levels of anandamide.

Anandamide – The “Bliss” Molecule of the Endocannabinoid System

In 2015, a study examining both humans and rodents, found that high levels of anandamide contributed to mood elevation and fear reduction. When the enzymes that break down anandamide were inhibited, the subjects felt less fear and anxiety where threats were perceived.

2009 study linked anandamide to fertility by showing that high levels of this endocannabinoid were not only beneficial, but essential for regular ovulation and proper fetal development. The study also concluded that higher levels of anandamide during times of ovulation contributed to a healthy and successful pregnancy.

A slightly older study published in 2004 found that increased levels of anandamide the bloodstream created a “euphoric high” in people who had just performed rigorous exercise or physical activity. This is frequently described as a “runner’s high” or “adrenaline high”, and it’s likely the reason why people who use cannabis often feel that it contributes to their workout.

Although this is one of the more studied cannabinoids, there is still a lot that remains unknown about the bliss molecule the extent of its functions.

Clinical Endocannabinoid Deficiency

Clinical endocannabinoid deficiency is a recently discovered condition, some might call it a theory still, in which the body doesn’t produce enough endocannabinoids. As a result, the body becomes unbalanced leading to the onset of numerous different diseases and disorders.

According to acclaimed cannabinoid researcher Dr. Ethan Russo, people who are diagnosed with a clinical endocannabinoid deficiency can benefit tremendously by supplementing with phytocannabinoids – cannabinoids coming from plants.

Are You Suffering From Clinical Endocannabinoid Deficiency?

Migrainefibromyalgiairritable bowel syndrome and related conditions display common clinical, biochemical and pathophysiological patterns that suggests a clinical endocannabinoid deficiency that may be suitably treated with cannabinoid medicines,” Russo mentioned in his 2004 study. This research has been reviewed and echoed a couple times over the years, in 2014 and 2016.

The above conditions have the greatest evidence of being caused by a clinical endocannabinoid deficiency, however, there is an extensive and varied list of disorders that are likely related to this condition. These include neonatal failure to thrive, cystic fibrosis, causalgia, brachial plexopathy, phantom limb pain, infantile colic, glaucoma, dysmenorrhea, hyperemesis gravidarum, unexplained repetitive miscarriages, post-traumatic stress disorder, bipolar disease, and the list continues.

Neurological disorders have also been linked to a lack of natural endocannabinoids. Some experts believe that Alzheimer’s diseaseParkinson’s disease, and similar disorders can be treated with cannabinoids. This could be why people suffering from these conditions report success when self-medicating with cannabis products.

Final Thoughts

When you look at the whole picture, and realize how integrated cannabinoids are within almost every system in our bodies, it makes perfect sense why cannabinoid-based therapies are so successful at treating so many different conditions. The Endocannabinoid System has a role in all of our basic body functions, so if you’re feeling out of balance, can’t eat right, can’t sleep, suffering from anxiety, etc., the right blend of cannabinoids might be more effective than chemical pharmaceuticals at relieving your ailments and symptoms.

Thanks for stopping by CBDtesters.co, where we’re covering everything related to medical cannabis and legal cannabis business. Stop back frequently and subscribe to the Medical Cannabis Weekly Newsletter to keep yourself up-to-date.

The post The Endocannabinoid System Explained – Why Cannabis Is Good for Our Bodies appeared first on CBD Testers.

Is it possible to boost your Endocannabinoid System without Cannabis?

The world is facing some pretty big problems right now and it’s hard to think about little else. At a time like this, why should anyone turn their attention to their endocannabinoid system? There are so many reasons! Not only does it help regulate your immune system, but it also helps to manage stress, pain, […]

The post Is it possible to boost your Endocannabinoid System without Cannabis? appeared first on Latest Cannabis News Today – Headlines, Videos & Stocks.

The Medical Cannabis Weekly Newsletter: Is Cannabis Use Destroying Your Teeth? Cannabis and Periodontal Disease, THC and Menstruation and more

When we think about the possible health risks associated with cannabis, periodontal disease is not usually high on the list… but maybe it should be. 

Also, due to hormone and endocannabinoid fluctuation, it turns out some women might need more cannabis than usual to alleviate painful symptoms. And when it comes to sleep – what works best, cannabinoids or melatonin? All that and more in this week’s Medical Cannabis Weekly Newsletter. 

Don’t forget to subscribe to our medical cannabis newsletter, below. Enjoy!

FEATURED STORY: Is Cannabis Use Destroying Your Teeth?

cannabis teeth

In a large-scale study commissioned by Duke University, researchers observed the dental health of regular cannabis users, and the results weren’t very reassuring. The study looked at 1,000 New Zealanders who had been using cannabis for more than 20 years.

Thankfully, there were no adverse health effects when it came to lung function, blood pressure, cholesterol, and weight – however, the health and gums seemed to suffer. Researchers made sure to account for any confounding factors such as poor hygiene and the use of tobacco, alcohol, or illicit drugs.

Click here to read the full story 

Subscribe to the Medical Cannabis Weekly Newsletter 


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New Advertising Packages from CBD Testers

We have multiple different advertising packages to work with your every need: A product launch campaign to get your brand in front of a larger audience, a CBD Flowers Program which is truly the best way to market your Hemp Buds, and a CBD Testers Program in which our very own CBD Product Testers will sample your products and write reviews! Check out our page for more details.

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Why You Might Need Extra Cannabis During Menstruation

cannabis menstruation

Menstrual cramps, endometriosis, and other cycle-related pain can be downright horrible. The pain can be completely debilitating because of its intensity. Many of us will reach straight for the buds (or vape, edibles, whatever you prefer) only to find that they’re not working their usual magic. As it turns out, there’s a scientific reason for this.

Click here to read the full story 

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Cannabinoids vs Melatonin – What’s the Best Sleep Aid?

cannabinoids vs. melatonin

Are you one of millions of Americans suffering from sleep deprivation? If so, a supplemental sleep aid might be just what you need to get in some more zzz’s and improve your overall health. But what will be more effective: Cannabis or Melatonin?

Click here to read the full story 

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Other Trending News:

The post The Medical Cannabis Weekly Newsletter: Is Cannabis Use Destroying Your Teeth? Cannabis and Periodontal Disease, THC and Menstruation and more appeared first on CBD Testers.

Why You Might Need Extra Cannabis During Menstruation

Ladies, if you’ve ever felt like cannabis doesn’t cut it like usual during your period; well don’t worry, you’re not alone and it’s not in your head.

Menstrual cramps, endometriosis, and other cycle-related pain can be downright horrible. The pain can be completely debilitating because of its intensity. Many of us will reach straight for the buds (or vape, edibles, whatever you prefer) only to find that they’re not working their usual magic. As it turns out, there’s a scientific reason for this.

There is an endocannabinoid called anandamide – or The Bliss Molecule – which is responsible for regulating many different systems in our bodies. Included in anandamide’s role is to reduce stress and thus, increase happiness and “blissfulness”. Apparently, anandamide levels vary tremendously during the menstrual cycle, making the symptoms of pain more intense and the effect of cannabis less powerful.


Another factor is the low levels of estrogen in our bodies during menstruation. When estrogen levels are low, the body doesn’t metabolize THC very well and makes it almost useless for some women. When estrogen levels are higher, THC is quickly broken down, making it more potent. The reason for this needs to be studied further.

It’s important to remember that while this does seem to be increasingly common for some women, not everyone will have the same experience. Some ladies feel absolutely no difference when using cannabis during menstruation as opposed to any other time of the month.  

“Some women may find that they may require a little more cannabis to improve their symptoms prior to, during, and directly after menstruation,” said Marissa Fratoni, RN-BSN in an interview with High Times Magazine. “Some women may need to use cannabis minimally to improve the symptoms they experience during this time.”

If you are someone that’s sensitive to THC during your period, try taking a break from regular cannabis buds and try some CBD-dominant strains (or products) instead. Not only does CBD have no psychoactive effects, but it’s known to counteract the effects of THC – so it can be beneficial in many ways.

At the end of the day, there is no one-size-fits-all solution to managing menstrual pain. But it’s important to know why your body might be reacting a certain way to different remedies.

For more articles like this one, subscribe to the Medical Cannabis Weekly Newsletter.

The post Why You Might Need Extra Cannabis During Menstruation appeared first on CBD Testers.

Can CBD and Cannabigerol (CBG) create A Cannabinoid Powerhouse?

Cannabigerol (CBG) can compliment cannabidiol (CBD) in many ways. On its own without a supportive sprectrum, cannabidiol can make certain people feel almost a little unpleasant. Many causes are behind this. One reason is it only activates half of the cannabinoid system. A marriage of cannabinoids will work together to uplift the system in a […]

The post Can CBD and Cannabigerol (CBG) create A Cannabinoid Powerhouse? appeared first on Cannabis News | Lifestyle Tips | Expert Opinions | Stocks.